HEALTHY PARTICIPANTS

This early-stage study tests a new vaccine called VXB-251 in 240 healthy adults aged 60-83. The vaccine aims to protect against three viruses that cause serious lung infections: RSV, hMPV, and PIV3. Researchers will check if the vaccine is safe and triggers a strong immune respon…

This study tests two herbal supplements, CL19183 and CL24212, to see if they help overweight adults lose weight and improve metabolic health. About 150 healthy but overweight participants (BMI 25-30) aged 25-55 will take the supplements or a placebo, while also following a standa…

This early-stage study tests a new drug called AZD0780 in 40 healthy adults with high LDL (bad) cholesterol. The goal is to see if it safely lowers cholesterol levels compared to a placebo. Participants take the drug or placebo by mouth and are monitored for side effects and how …

This study tests whether giving a new long-acting antiviral medicine (CD388) together with the high-dose flu vaccine is safe and does not weaken the body's immune response. About 100 healthy adults aged 18-49 will receive either the vaccine plus CD388 or the vaccine plus a placeb…

This study tests whether a virtual reality (VR) game can help primary schoolchildren aged 6-12 learn and practice better hygiene to prevent COVID-19 and other respiratory infections. Over 2,000 children will either play the VR game for two weeks or receive no extra training. Rese…

This study looks at whether giving the experimental drug CD388 every year is safe for healthy adults. About 400 people who already received one dose without problems will get two more annual doses. Researchers will monitor for side effects and check if the body makes antibodies a…

This study looked at whether taking magnesium citrate (400 mg daily for 90 days) could improve sleep quality and thinking skills in healthy Saudi adults who had poor sleep. 41 people took part, and researchers compared them to a group that didn't take any supplement. The goal was…

This study compares a newer gum surgery technique (gingivalstat) to the standard crown lengthening for people with a gummy smile caused by altered passive eruption. The goal is to see which method keeps the gum line more stable over 6 months after surgery. Twenty-two healthy adul…

This study looks at how a new drug called AZD5004 changes the way the body processes two diabetes drugs, mitiglinide and pioglitazone. It involves 32 healthy adults and aims to measure drug levels and safety. The results will help guide proper dosing in future studies.

This early-phase study tests the safety and how the body processes a single dose of the experimental drug AZD0292 in 18 healthy Japanese adults. Participants receive either the drug or a placebo by IV infusion. The main goal is to check for side effects and measure drug levels in…

This study looks at whether a special breathing warm-up can improve muscle strength in athletes during exercise. About 28 trained athletes aged 14-30 will try three different warm-up routines: a breathing warm-up, a fake (placebo) breathing warm-up, and no warm-up at all. The goa…

This study looks at how two common drugs—carbamazepine (a CYP3A4 inducer) and itraconazole (a CYP3A4 inhibitor)—change the way the body processes a single dose of AP31969. It involves 28 healthy adults aged 18 to 55. The goal is to understand potential drug interactions, not to t…

This study aims to figure out the ideal number of follow-up visits for people who wear contact lenses. Researchers will track 300 healthy adults aged 18 to 40 who are new or experienced lens wearers. The goal is to ensure safe and comfortable lens use without unnecessary trips to…

This early-stage study tests different versions of an experimental drug called AZD6234 in 21 healthy adults with overweight or obesity. The goal is to see which formulation gets into the blood best and causes the fewest side effects. Participants receive a single injection and ar…

This early-stage study tests a new drug called STAR-0310 in healthy adults to see if it is safe and how the body processes it. About 40 participants will receive either a single dose of the drug or a placebo. The study aims to gather initial safety data before testing in patients…

This study tests a new drug called QL2106 against an approved drug, Tremfye®, in 190 healthy adults aged 18-45. The goal is to compare how the body processes each drug, their safety, and any immune reactions. Participants receive a single dose and are monitored closely. This is a…

This study tracks how the experimental drug AZD4144 moves through the body in 8 healthy men aged 30–65. Participants receive a single dose either by mouth or injection, with a tiny radioactive tag to follow the drug's breakdown and elimination. The goal is to understand absorptio…

This study involves 400 healthy adults aged 60-85 to test new computerized measures of thinking and daily function. Participants are randomly assigned to take either the new tests or standard tests over one year. The goal is to see if the new tests are better at detecting early c…

This study looks at whether four one-hour coaching sessions with a psycho-oncologist can help doctors and nurses who treat cancer patients. The goal is to improve how they communicate with patients and handle their own stress. The study will involve 62 physicians and nurses from …

This study was designed to check if new combination tablets of nirmatrelvir and ritonavir work the same as the already-approved Paxlovid tablets. Healthy adults would have received single doses of different tablet forms under fasting conditions, and blood samples would have been …

This study looks at brain activity and heart rhythms in 45 people—some who have had a stroke and some who are healthy. Researchers use special head sensors (fNIRS and EEG) and heart monitors (ECG) to measure differences while participants rest with their eyes closed. The goal is …

This early-stage study tests a new drug called INCA033989 in 72 healthy adults aged 18 to 55. The goal is to see how the drug moves through the body and whether it is safe when given as a shot or through an IV. No treatment benefit is expected; the study simply gathers important …

This study looks at how a single session of Swedish massage or light touch changes brain activity, heart rate, blood pressure, breathing, and mood in healthy adults. Thirty participants will be randomly assigned to receive either massage or light touch. Brain scans (MRI) are done…

This study tests whether using a simple pillow can be as effective as a standard manikin for teaching CPR to non-healthcare professionals. Researchers will compare chest compression depth, number, and hand position in 128 healthy adults. If successful, pillows could offer a low-c…

This study looks at whether a special education program on patient safety can shift how nursing leaders and educators in Saudi Arabia think about safety culture. About 102 head nurses, assistant head nurses, and educators will take a survey before the training, then again 3 and 6…

This study tests whether a single tablet containing both laroprovstat and rosuvastatin works as well as taking the two drugs separately. It involves 44 healthy adults aged 18 to 55 who will receive different doses in a crossover design. The goal is to measure how much of each dru…

This early-stage study tests whether mRNA-0184 is safe in 52 healthy adults. Participants receive one or more doses under the skin. The goal is to check for side effects and measure how the drug moves through the body. No treatment or direct benefit is expected.

This study tests three different tablet versions of an experimental drug called LY4100511 in 48 healthy adults. Researchers want to see how well each version is absorbed by the body, and whether taking a common stomach acid medication changes that absorption. The goal is to pick …

This pilot study looked at whether listening to self-chosen Levantine music can change how healthy young adults feel pressure pain. 32 participants were tested in silence and while listening to their own music. The goal was to see if music can help reduce pain sensitivity and imp…

This study tests whether a new biosimilar medicine called CT-P52 behaves like the approved drug Taltz in the body. It involves 218 healthy adults aged 19 to 55 who receive a single dose. The goal is to check if the two drugs are similar in terms of safety and how they are process…

This study looks at whether doing very short, intense bike sprints (just 10–20 seconds, once or twice per session, two days a week) can improve heart and lung fitness in inactive adults. Sixty healthy but inactive participants will do these sprints for 9 weeks, and their results …

This study tests whether focused ultrasound can alter the effects of propofol, a common anesthesia drug, on the brain. Ten healthy adults will receive both real and fake ultrasound while under sedation. Researchers will measure brain signals and responsiveness to commands to unde…

This early-stage study is testing a single injection of a new drug called AG-236 in 24 healthy adults aged 18 to 55. The main goal is to check for side effects and see how the drug moves through the body. No treatment for any disease is being tested here.