Could a single pill replace two? early study tests combo drug

NCT ID NCT07622433

Ongoing Knowledge-focused Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 29, 2026 · Updated 2 times

Summary

This early-stage trial is testing whether a single tablet containing both laroprovstat and ezetimibe works as well as taking the two drugs separately. The study involves 18 healthy adults who will receive different pill combinations in random order. Researchers will measure how the drugs are absorbed and processed by the body, and whether food affects absorption. The goal is to see if a combined pill is a viable option for future use.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Laroprovstat and ezetimibe (combined and separate tablets)
What this could lead to: If successful, this could lead to a single pill that simplifies taking both drugs together, potentially improving convenience for future patients.
What could go wrong: This is a very early Phase 1 study in only 18 healthy people. It only checks how the body handles the drugs, not if they work for any disease. Results may not apply to patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Dyslipidemias hyperlipidemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY PARTICIPANTS

Contacts and locations

Locations

Research Site

Brooklyn, Maryland, 21225, United States

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