HEALTHY PARTICIPANTS

This study aims to help 16,000 college students in Zimbabwe take charge of their own sexual health using a mobile phone tool. The tool includes decision aids to guide choices about HIV prevention and contraception. Researchers will test whether this approach increases the use of …

This early-stage study tests a new drug called QL2302 in 178 healthy adults aged 18-45. It compares how the body processes QL2302 versus the approved drug Tezspire, and checks for side effects. The goal is to see if QL2302 works similarly, not to treat any disease.

This study looks at how a special nutritional drink affects blood sugar levels in healthy adults. Thirty participants will drink both the test supplement and a sugar solution on different days to compare their effects. The goal is to measure the drink's glycemic index, which tell…

This study looks at how the brain uses feedback to control speech in 90 adults aged 18-50, including people who stutter, have dyslexia, and those with typical speech. Participants will do speech tasks, have MRI scans, and receive mild brain stimulation to understand differences i…

This study looks at how different breathing patterns during strength exercises affect eye pressure and the tiny blood vessels in the retina. Researchers will measure these changes in 60 healthy adults aged 18-40 while they perform isokinetic and isometric exercises. The goal is t…

This early-stage study tests whether an experimental inhaled powder called SYH2059 is safe and how it moves through the body. It involves 84 healthy adults aged 18 to 55. The study is not intended to treat any disease, but to gather important safety information for future researc…

This study aims to better understand how brain stimulation (TMS) affects the prefrontal cortex, a key area for mood and thinking. Researchers will use advanced MRI and EEG in 34 healthy adults to map brain connections. The goal is to improve targeting for depression treatments, w…

This study tracks how gut bacteria and their byproducts change over a year in 100 adults who have gastric bypass surgery. Researchers compare these changes to those in people with obesity on diet alone and healthy-weight individuals. The goal is to understand which bacterial shif…

This early-stage study will test a single dose of the experimental drug STLX-2012 in 32 healthy volunteers aged 18 to 55. The main goal is to see if the drug is safe and how the body processes it. Participants will be randomly assigned to receive either the drug or a placebo, and…

This study compares three fiber supplements—LOAM prebiotic fiber, inulin, and a placebo—to see which causes the least gas and digestive discomfort. Healthy adults who eat a low-fiber diet will take one supplement daily for four weeks and wear a small device that tracks gas. The g…

This study tests how the body processes two different forms of the drug evolocumab in 400 healthy adults aged 18 to 60. Participants receive a single dose and are monitored for drug levels and side effects over about two months. The goal is to see if the forms are similar, not to…

This study tests whether a gentle, non-invasive electrical stimulation applied to the brain during sleep can temporarily change brain activity patterns, specifically sleep spindles. About 24 healthy adults will each spend 3 nights in a sleep lab to compare real stimulation agains…

This early-stage study tests a new drug, AK0406, in 32 healthy adults to see if it is safe and how the body processes it. Participants receive a single dose of either the drug or a placebo. The goal is to gather initial safety information before testing in patients.

This early-stage study tests the safety and how the body handles a new drug called NBX-100 in 8 healthy adults aged 21-50. Participants receive four weekly doses and have frequent check-ups, including blood tests and psychological assessments. The goal is to gather safety and dru…

This early-stage study tests whether IBI3033 is safe and how the body processes it. Eight healthy Chinese adults will receive either the drug or a placebo. The goal is to check for side effects and measure drug levels in the blood, not to treat any disease.

This study will compare two different versions of an oral remdesivir drug in 48 healthy Chinese adults. Participants will receive both forms at different times to see how the body absorbs and processes each one. The goal is to understand if the new formulation works similarly to …

This study works with African Methodist Episcopal (AME) churches in South Carolina to help older adults (50+) become more active. The program, called Walk Your Heart to Health, includes walking groups and healthy eating support. Researchers will study what helps or hinders puttin…

This study looks at how plant sterols (natural compounds found in plants) affect a newly discovered gene called GPR146, which helps control cholesterol. Researchers will give 23 healthy adults three different test meals and measure gene activity in their blood and gut cells. The …

This study looks at how different amounts and types of manual pressure (like massage) affect the body in 90 healthy adults. Participants will receive pressure on their upper back while researchers measure heart rate, stress hormones, pain sensitivity, and blood flow. The goal is …

This study aims to collect healthy organ measurements—like liver fat and stiffness—from 50 healthy adults in Singapore. Participants will undergo an MRI scan. The goal is to create reference ranges that may differ by ethnicity, helping doctors better interpret future test results…

This study tests whether a mild electrical pulse to the ear (taVNS) can temporarily improve attention, memory, and other thinking skills in 60 healthy adults aged 18-30. Each person will receive both the real stimulation and a fake (sham) version in separate sessions to compare e…

This early-phase study tests the safety and how the body handles a single dose of IBI3033 in 32 healthy Chinese adults. Participants receive either the drug or a placebo and are monitored for side effects and drug levels over 12 weeks. The goal is to gather safety data, not to tr…

This study compares how well people with migraine can imagine movements (motor imagery) compared to healthy individuals. Researchers will also look at how these mental abilities relate to body awareness, balance, anxiety, and depression. About 136 adults aged 18-65 will participa…

This study compares two ways of doing a therapy exercise: using imagination or using virtual reality (VR). Healthy student volunteers will try both versions and report how they feel. The goal is to see if VR makes the exercise easier or more effective, especially for people who h…

This study looks at whether exercising in the morning or evening changes how we feel pain. Healthy adults aged 18-40 will do exercise sessions at different times and have their pain thresholds measured. The goal is to understand if our body's internal clock affects pain relief fr…

This study gives 50 healthy adults a one-time dose of psilocybin (the active ingredient in magic mushrooms) or a placebo to see how it changes brain waves, blood chemicals, and feelings like empathy. Participants must have never used psychedelics before. The goal is to understand…

This study looks at what makes it easier or harder for Turkish young people (ages 15-24) to be physically active. Researchers will survey 318 healthy volunteers about their activity levels, stress, and daytime sleepiness. The goal is to understand these factors so better programs…

This study looks at whether a special warm-up that includes balance and coordination exercises works better than a standard warm-up for improving balance and strength in people who go to the gym regularly. About 46 healthy adults aged 18 to 40 will take part in 6 weeks of warm-up…

This study checks if two different tablet forms of the drug navlimetostat (wet-granulation vs. dry-granulation) are absorbed the same way in the body. It involves 64 healthy adult women who are not able to have children. Participants will take both tablet forms at different times…