Gut bacteria secrets after Weight-Loss surgery revealed in new study

NCT ID NCT07381140

Not yet recruiting Knowledge-focused Sponsor: Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This observational study tracks 100 adults to see how Roux-en-Y gastric bypass surgery changes gut bacteria and related metabolic products over 12 months. Participants include people having surgery, those with obesity on diet alone, and healthy normal-weight individuals. Researchers will compare stool and blood samples to understand links between gut changes, weight loss, and health improvements.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help identify gut bacteria patterns that predict better weight loss and metabolic health after gastric bypass surgery.
What could go wrong: This is an observational study, not a treatment trial. It will not test any new therapy, and results may not lead to direct clinical changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GUT MICROBIOTA HEALTHY PARTICIPANTS OBESE PATIENTS OBESE PATIENTS WITH BARIATRIC SURGERY

Contacts and locations

Locations

Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis

Castellana Grotte, BA, 70013, Italy

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