GUT -MICROBIOTA

This study tests whether a daily supplement containing a specific probiotic, tryptophan, and branched-chain amino acids can slow the progression of early-stage Parkinson's disease. Researchers will recruit 120 participants and randomly assign them to receive either the supplement…

This study tests whether a 12-week course of a multi-species synbiotic supplement can lower harmful gut toxins and reduce inflammation in adults on hemodialysis. About 30 participants will take the supplement and have their blood and urine levels of toxins and inflammatory marker…

This study is testing whether a 12-week course of a multi-species synbiotic (a mix of probiotics and prebiotics) can improve gut health and reduce harmful toxins in the blood of people on hemodialysis. The trial will enroll 30 adults who have been on dialysis for at least 3 month…

This study tests whether eating peanuts and peanut products daily for six months can improve blood sugar, blood pressure, thinking skills, and gut health in people with prediabetes. Researchers will enroll 72 adults from diverse racial backgrounds. Participants will eat different…

This study tests whether a daily dose of freeze-dried wild blueberry powder can improve blood sugar, blood pressure, and brain function in women with prediabetes. Thirty overweight women aged 20-65 will take either the blueberry powder or a placebo for six weeks. Researchers will…

This study is testing whether lifestyle changes—like following a Mediterranean diet, exercising regularly, or doing cognitive training—can prevent cognitive decline and improve mood in people aged 50 to 80 who have depressive symptoms or major depression but no current memory pro…

This study tests whether a daily snack rich in plant chemicals and fibre can ease perimenopause symptoms like hot flushes, mood changes, and sleep problems. Twenty women aged 40-55 who are not on hormone therapy will eat either the special snack or a placebo for several weeks, th…

This study tests a special infant formula designed for babies with cow's milk protein allergy. The formula includes added prebiotics, probiotics, and a human milk oligosaccharide to help ease allergy symptoms. About 41 infants under 10 months old will use the formula for 4 weeks,…

This study tests whether eating freeze-dried wild blueberry powder every day for 12 weeks can improve gut health, reduce inflammation, and ease joint pain in adults with arthritis. Fifty participants will take either the blueberry powder or a placebo, with a 2-week break between …

This study creates miniature, lab-grown versions of liver cancer tumors from patient biopsies. Researchers will test how well different treatments work on these models and look at how gut health and the tumor's environment affect the disease. The goal is to better understand live…

This study looks at how pesticides and the bacteria in your gut and genital tract might be linked to endometriosis and infertility. Researchers will compare 160 women with and without endometriosis to find patterns in their DNA and bacteria. The goal is to better understand the d…

This study looks at how eating dairy yogurt or plant-based yogurt for 12 weeks affects body composition, bone density, and gut bacteria in overweight postmenopausal women. Participants will follow a weight-loss diet and be randomly assigned to eat two servings of dairy yogurt, pl…

This study looks at how eating foods made with alternative proteins—like insects, microalgae, hemp, and legumes—affects hunger, fullness, and health. About 40 adults, some with overweight, will try these foods in a controlled setting. Researchers will measure appetite, blood suga…

This study looks at how the bacteria in your gut might affect epilepsy that doesn't get better with standard medicines. Researchers will follow 120 people aged 3 to 50 who have drug-resistant epilepsy and are starting a new treatment like surgery or a special diet. The goal is to…

This study is looking at whether the bacteria in your gut can predict how well a combination of immunotherapy and chemotherapy works for advanced stomach cancer. Researchers will track 300 patients and check their gut bacteria at several points during treatment. The goal is to fi…

This study looks at whether replacing a narrowed heart valve (TAVI) changes the types of bacteria living in the gut. Researchers will collect stool and blood samples from 40 patients before and after the procedure. The goal is to see if improved blood flow from the new valve help…

This study tests a tiny, swallowable device called a mini-pill that collects samples from different parts of the gut. Researchers want to see if it can show how eating meat versus plant-based meat alternatives changes gut bacteria and health markers. Thirty men and postmenopausal…

This study tests if giving C-section babies bacteria from their mother can help restore their gut health to be more like babies born vaginally. About 100 healthy infants will receive a daily oral bacterial product for one or four weeks. Researchers will compare their gut bacteria…