Heart surgery may reshape your gut microbiome

NCT ID NCT07052071

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether replacing a narrowed heart valve (TAVI) changes the types of bacteria living in the gut. Researchers will collect stool and blood samples from 40 patients before and after the procedure. The goal is to see if improved blood flow from the new valve helps restore a healthier gut microbiome, which could open new doors for heart disease treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Transcatheter Aortic Valve Implantation (TAVI) procedure

What this could lead to

If successful, this could reveal a connection between heart function and gut health, pointing toward new ways to treat cardiovascular disease by targeting the microbiome.

What could go wrong

This is a small, early observational study with only 40 participants. It looks at changes in gut bacteria, not direct treatment outcomes, so results may not lead to immediate medical advances.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

aortic valve stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hippokration General Hospital of Athens

    RECRUITING

    Athens, Greece

    Contact Phone: •••-•••-•••• Email: •••••@•••••