ESOPHAGEAL CANCER

This study is testing if adding an immunotherapy drug called QL1706 to standard chemotherapy can help shrink tumors in people with a hard-to-treat form of esophageal cancer. The goal is to make surgery more successful. About 24 participants in China will receive the drug combinat…

This study is testing if adding a precise, high-dose radiation treatment (SBRT) to standard chemotherapy and immunotherapy helps people with esophageal cancer that has spread to a few other places in the body. It aims to better control the cancer and help patients live longer wit…

This early-stage study is testing the safety of a new two-part treatment for people with advanced head & neck cancer or a type of esophageal cancer that has returned or spread. The treatment involves injecting a modified virus directly into a tumor to block its blood supply, whil…

This study is testing if a drug called toripalimab can help prevent esophageal cancer from returning after surgery. It will involve 435 patients who have already had surgery to remove their cancer. Some patients will receive the drug for up to a year after surgery, while others w…

This study is for people with a type of esophageal cancer who have just finished standard chemoradiation treatment. It tests whether taking two drugs (toripalimab and capecitabine) for a longer period as 'maintenance therapy' can help keep the cancer from growing back and help pa…

This study is testing if a special fluorescent dye can help surgeons see and protect a critical nerve during esophageal cancer surgery. The nerve controls the voice box, and damaging it is a common complication. Researchers will compare surgery using the dye-guided imaging system…

This trial is testing a new robotic surgery system that allows surgeons to perform operations remotely. It will be used on patients needing surgery for cancers like colorectal or esophageal cancer, as well as other procedures in urology, gynecology, and general surgery. The main …

This early-stage study is testing a new cell-based treatment called SL-28 in adults with advanced solid tumors that have not responded to standard therapies. The main goals are to find the safest and most effective dose and to check for side effects. Participants will receive the…

This study is testing a new surgical technique designed to lower the risk of dangerous leaks where the stomach is reconnected to the esophagus after cancer removal. It will involve 73 adults with esophageal cancer undergoing a specific type of minimally invasive surgery. The tech…

This study aims to see if a personalized treatment plan can prevent esophageal cancer from coming back after surgery. It will enroll 172 patients who have had their cancer surgically removed but still have tiny amounts of cancer DNA in their blood, putting them at high risk for r…

This study is testing if freezing a tumor with liquid nitrogen before starting standard chemotherapy helps people with locally advanced esophageal cancer. Researchers want to see if this two-step approach leads to a better response and helps the body's immune system fight the can…

This study is testing a special fluorescent dye to help surgeons see which lymph nodes might contain cancer during surgery for esophageal cancer. The goal is to remove only the necessary lymph nodes, potentially reducing complications and recovery time. Researchers will compare t…

This study is testing a new program designed to help patients manage symptoms after surgery for esophageal cancer. The program uses a manual and continuous care procedures to guide recovery. Researchers will compare outcomes between patients who use the program and those who rece…

This study compares two different pain control methods for patients recovering from minimally invasive esophageal cancer surgery. Researchers want to see if a newer method called paravertebral catheter provides similar pain relief to the current standard method while potentially …

This study aims to develop an artificial intelligence (AI) tool to help doctors choose the best treatment for people with esophageal cancer. It will analyze thousands of patient scans and tissue samples to learn which treatments lead to the best outcomes. The goal is to create a …

This study is testing a new imaging technique to help doctors predict which esophageal cancer patients will respond to immunotherapy. Researchers will use special 'glow-in-the-dark' tracers and a camera during an endoscopy to look for specific proteins in the tumor. The goal is t…