Lymph node clues may predict immunotherapy response in esophageal cancer

NCT ID NCT07573397

Not yet recruiting Knowledge-focused Sponsor: Fudan University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will check if certain immune cells, called precursor exhausted T cells, found in cancer-free lymph nodes can predict whether esophageal cancer completely disappears after immunotherapy. Researchers will study 88 patients before surgery to see if these cells are better at predicting treatment success than current methods. The goal is to improve how doctors choose treatments for esophageal cancer patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors predict which esophageal cancer patients will benefit most from immunotherapy before surgery, leading to more personalized treatment.
What could go wrong: This is an early observational study with only 88 participants, so results may not apply to everyone. It is not testing a new treatment, only looking for a predictive marker.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

esophageal cancer Esophageal Neoplasms esophageal squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ESOPHAGEAL CANCER

More trials for these conditions

Other studies related to the condition(s) this trial covers.