DIFFUSE LARGE B CELL LYMPHOMA
Clinical trials for DIFFUSE LARGE B CELL LYMPHOMA explained in plain language.
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New drug trio aims to replace chemo for aggressive lymphoma
Disease control Not yet recruitingThis study tests a combination of three drugs (polatuzumab vedotin, glofitamab, and tafasitamab) as a first treatment for people with aggressive B-cell lymphomas, aiming to avoid standard chemotherapy. About 30 adults with newly diagnosed diffuse large B-cell lymphoma or high-gra…
Matched conditions: DIFFUSE LARGE B CELL LYMPHOMA
Phase: PHASE2 • Sponsor: Brown University • Aim: Disease control
Last updated May 17, 2026 04:28 UTC
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New hope for lymphoma patients: drug may keep cancer in check
Disease control Not yet recruitingThis study tests a drug called chidamide in people with a fast-growing type of lymphoma (double-expressor DLBCL) who are in remission but still have tiny traces of cancer DNA in their blood. The goal is to see if taking chidamide for up to 2 years can clear those traces and keep …
Matched conditions: DIFFUSE LARGE B CELL LYMPHOMA
Phase: PHASE2 • Sponsor: Rong Tao • Aim: Disease control
Last updated May 17, 2026 04:27 UTC
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Personalized radiation boosts lymphoma therapy in new trial
Disease control Not yet recruitingThis study tests a new way to treat diffuse large B-cell lymphoma by using a blood test to find leftover cancer cells early. Patients with detectable cancer after two chemo cycles get low-dose radiation to those spots, while others continue standard care. The goal is to see if th…
Matched conditions: DIFFUSE LARGE B CELL LYMPHOMA
Phase: PHASE2 • Sponsor: University of Nebraska • Aim: Disease control
Last updated May 17, 2026 04:26 UTC
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New combo attack on stubborn lymphoma: radiation plus immune-boosting antibody
Disease control Not yet recruitingThis early-stage trial is testing whether giving radiation therapy before a bispecific antibody drug (epcoritamab or glofitamab) is safe for people with diffuse large B-cell lymphoma that has come back or not responded to at least two prior treatments. The study will enroll 12 ad…
Matched conditions: DIFFUSE LARGE B CELL LYMPHOMA
Phase: PHASE1 • Sponsor: University of Utah • Aim: Disease control
Last updated May 13, 2026 16:03 UTC
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Immune cell army targets Hard-to-Treat lymphoma
Disease control Not yet recruitingThis early-phase trial tests a new treatment for people with B-cell non-Hodgkin lymphoma that has not responded to at least two prior therapies. Participants receive donor immune cells (NK cells) along with two antibody drugs (rituximab and tafasitamab) to help the body fight the…
Matched conditions: DIFFUSE LARGE B CELL LYMPHOMA
Phase: PHASE1 • Sponsor: Paolo Caimi, MD • Aim: Disease control
Last updated May 13, 2026 16:01 UTC
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New hope for Tough-to-Treat lymphoma: drug combo trial launches
Disease control Not yet recruitingThis study tests a new combination of drugs for adults with diffuse large B-cell lymphoma that has come back or not responded to standard treatments. The goal is to see if adding homoharringtonine and a BCL-2 inhibitor to rituximab and prednisone can safely shrink tumors. About 6…
Matched conditions: DIFFUSE LARGE B CELL LYMPHOMA
Phase: PHASE1, PHASE2 • Sponsor: First Affiliated Hospital of Zhejiang University • Aim: Disease control
Last updated May 13, 2026 15:58 UTC
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New CAR-T therapy targets tough lymphoma in early trial
Disease control Not yet recruitingThis early-phase study tests a new treatment called CY-219 CAR-T cells for people with B-cell lymphoma that has come back or not responded to standard therapy. The treatment uses a patient's own immune cells, modified to attack cancer cells. The main goals are to check safety and…
Matched conditions: DIFFUSE LARGE B CELL LYMPHOMA
Phase: PHASE1 • Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated May 12, 2026 13:40 UTC
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Elderly lymphoma patients may get better care with Geriatric-Guided plan
Symptom relief Not yet recruitingThis study compares a geriatric-guided care approach, which includes nutritional and rehabilitation support, to standard cancer treatment alone in elderly patients (70+) with diffuse large B-cell lymphoma. The goal is to see if this personalized plan improves quality of life and …
Matched conditions: DIFFUSE LARGE B CELL LYMPHOMA
Phase: NA • Sponsor: Fondazione Italiana Linfomi - ETS • Aim: Symptom relief
Last updated May 12, 2026 13:42 UTC