DIFFUSE LARGE B CELL LYMPHOMA
Clinical trials for DIFFUSE LARGE B CELL LYMPHOMA explained in plain language.
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Blood cancer transplant study tests safer GVHD prevention
Disease control TerminatedThis study looked at people with blood cancers receiving a stem cell transplant from an unrelated donor. The goal was to compare two drug combinations (cyclosporine plus sirolimus with either MMF or post-transplant cyclophosphamide) to prevent graft-versus-host disease (GVHD), a …
Matched conditions: DIFFUSE LARGE B CELL LYMPHOMA
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated May 17, 2026 02:02 UTC
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Lymphoma drug trial stopped early after enrolling only 5 patients
Disease control TerminatedThis study tested the drug pembrolizumab in people with a hard-to-treat type of lymphoma (DLBCL) that has certain gene changes (PD-L1 alterations). The goal was to see if the drug could shrink tumors. However, the study was stopped early and only 5 people took part, so the result…
Matched conditions: DIFFUSE LARGE B CELL LYMPHOMA
Phase: PHASE2 • Sponsor: University of Chicago • Aim: Disease control
Last updated May 17, 2026 02:01 UTC
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New drug combo targets tough cancers in early trial
Disease control TerminatedThis early-phase study tested a new medicine, PF-08046032, alone or with another drug (sasanlimab) in 6 adults with advanced lymphomas or solid tumors that had spread or stopped responding to standard treatments. The main goals were to check safety and find the right dose. The st…
Matched conditions: DIFFUSE LARGE B CELL LYMPHOMA
Phase: PHASE1 • Sponsor: Pfizer • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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New drug combo targets Hard-to-Treat lymphoma in patients who Can't have transplants
Disease control TerminatedThis study looked at combining two experimental drugs (maplirpacept and glofitamab) after a single dose of obinutuzumab for adults with diffuse large B-cell lymphoma that has come back or not responded to at least two prior treatments. Participants could not have a stem cell tran…
Matched conditions: DIFFUSE LARGE B CELL LYMPHOMA
Phase: PHASE1, PHASE2 • Sponsor: Pfizer • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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Promising lymphoma combo trial halted early
Disease control TerminatedThis study tested a new combination of drugs (polatuzumab vedotin plus standard chemotherapy) for people with diffuse large B-cell lymphoma that returned or didn't improve after initial treatment. The goal was to see if the new combo could shrink tumors better than standard thera…
Matched conditions: DIFFUSE LARGE B CELL LYMPHOMA
Phase: PHASE2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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Experimental lymphoma drug trial halted early after testing in just 14 patients
Disease control TerminatedThis study tested an experimental drug called SAR444245, alone or with another cancer drug, in people aged 12 and older with B cell lymphoma that returned or didn't respond to prior treatments. The goal was to see if the drug could shrink tumors. The trial was stopped early after…
Matched conditions: DIFFUSE LARGE B CELL LYMPHOMA
Phase: PHASE2 • Sponsor: Sanofi • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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Experimental combo for tough lymphoma shows early promise
Disease control TerminatedThis early-stage trial tested a combination of two drugs, tazemetostat and venetoclax, in people with Non-Hodgkin lymphoma that had returned or stopped responding to standard treatments. The main goals were to find the safest dose of venetoclax to use with tazemetostat and to see…
Matched conditions: DIFFUSE LARGE B CELL LYMPHOMA
Phase: PHASE1 • Sponsor: Weill Medical College of Cornell University • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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New hope for lymphoma patients who Can't get a transplant
Disease control TerminatedThis study tested a new three-drug combination for people with a type of blood cancer called diffuse large B-cell lymphoma that came back or didn't respond to prior treatment. Participants could not have a stem cell transplant or CAR-T therapy. The goal was to find a safe and eff…
Matched conditions: DIFFUSE LARGE B CELL LYMPHOMA
Phase: PHASE1, PHASE2 • Sponsor: Pfizer • Aim: Disease control
Last updated May 13, 2026 16:01 UTC