New drug combo shows promise against Hard-to-Treat lymphomas

NCT ID NCT03598608

First seen Jan 22, 2026 · Last updated May 14, 2026 · Updated 24 times

Summary

This study tested a combination of two drugs, favezelimab and pembrolizumab, in 137 people with Hodgkin lymphoma and other B-cell blood cancers. The goal was to see if the combo is safe and can shrink tumors. Participants received the drugs alone or together, and researchers monitored side effects and cancer response.

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Contacts and locations

Locations

  • A.O. Universitaria Policlinico S. Orsola-Malpighi ( Site 0351)

    Bologna, Emilia-Romagna, 40138, Italy

  • BC Cancer ( Site 0107)

    Vancouver, British Columbia, V5Z 1L3, Canada

  • Banner MD Anderson Cancer Center ( Site 0020)

    Gilbert, Arizona, 85234, United States

  • CancerCare Manitoba ( Site 0101)

    Winnipeg, Manitoba, R3E 0V9, Canada

  • Chaim Sheba Medical Center. ( Site 0380)

    Ramat Gan, 5262001, Israel

  • City of Hope ( Site 0001)

    Duarte, California, 91010, United States

  • Concord Repatriation & General Hospital ( Site 0203)

    Concord, New South Wales, 2139, Australia

  • Dana Farber Cancer Institute ( Site 0002)

    Boston, Massachusetts, 02215, United States

  • Fox Chase Cancer Center ( Site 0019)

    Philadelphia, Pennsylvania, 19111, United States

  • Hadassah Ein Karem Jerusalem ( Site 0383)

    Jerusalem, 9112001, Israel

  • Humanitas-U.O di Oncologia medica ed Ematologia ( Site 0352)

    Rozzano, Milano, 20089, Italy

  • Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori ( Site 0354)

    Meldola, Forli-Cesena, 47014, Italy

  • Jewish General Hospital ( Site 0105)

    Montreal, Quebec, H3T 1E2, Canada

  • Monash Health ( Site 0201)

    Clayton, Victoria, 3168, Australia

  • Pacific Cancer Care ( Site 0006)

    Monterey, California, 93940, United States

  • Princess Alexandra Hospital ( Site 0204)

    Woollongabba, Queensland, 4102, Australia

  • Princess Margaret Cancer Centre ( Site 0100)

    Toronto, Ontario, M5G 2M9, Canada

  • Rambam Medical Center ( Site 0382)

    Haifa, 3109601, Israel

  • Ronald Reagan UCLA Medical Center (Radiological Sciences) ( Site 0007)

    Los Angeles, California, 90095, United States

  • Sourasky Medical Center ( Site 0381)

    Tel Aviv, 6423906, Israel

  • St Vincent s Hospital (Melbourne) Limited ( Site 0202)

    Fitzroy, Victoria, 3065, Australia

  • Texas Oncology-Austin Midtown ( Site 8002)

    Austin, Texas, 78705, United States

  • U. klinikum Koeln AOER ( Site 0326)

    Cologne, North Rhine-Westphalia, 50937, Germany

  • Universitaetsklinikum Leipzig AOeR ( Site 0327)

    Leipzig, Saxony, 4103, Germany

  • University of California San Francisco ( Site 0023)

    San Francisco, California, 94143, United States

Conditions

Explore the condition pages connected to this study.