New cancer drug PRO1160 tested in advanced cancers – trial ends early

NCT ID NCT05721222

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a drug called PRO1160 in people with advanced kidney cancer, nasopharyngeal cancer, or non-Hodgkin lymphoma. The goal was to find a safe dose and see if the drug shrinks tumors. The trial was stopped early, so results are limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

PRO1160 (GEN1160)

What this could lead to

If successful, this could point toward a new treatment option for certain advanced cancers that have not responded to other therapies.

What could go wrong

This trial was terminated early, so results are limited. It is an early-phase study, so safety and effectiveness are not yet established.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diffuse large B-cell lymphoma follicular lymphoma mantle cell lymphoma nasopharyngeal carcinoma non-Hodgkin lymphoma nonpapillary renal cell carcinoma papillary renal cell carcinoma renal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cancer Hospital of Chinese Academy of Medical Sciences

    Beijing, Beijing Municipality, China

  • City of Hope Comprehensive Cancer Center - Duarte

    Duarte, California, 91010, United States

  • Cleveland Clinic - Euclid Hospital

    Cleveland, Ohio, 44195, United States

  • Fudan University Shanghai Cancer Center

    Shanghai, Shanghai Municipality, China

  • Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • Levine Cancer Center

    Charlotte, North Carolina, 28204, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Montefiore Medical Center - Montefiore Hospital

    The Bronx, New York, 10467, United States

  • NYU Langone Health

    New York, New York, 10016, United States

  • Oregon Health & Science University

    Portland, Oregon, 97239, United States

  • Providence Portland Medical Center

    Portland, Oregon, 97213, United States

  • Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

    Shanghai, Shanghai Municipality, China

  • START Mountain Cancer Center

    West Valley City, Utah, 84119, United States

  • Sarah Cannon Research Institute - Nashville

    Nashville, Tennessee, 37203, United States

  • The City of Hope Orange County Lennar Foundation Cancer Center

    Irvine, California, 92618, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • Washington University School of Medicine in St. Louis

    St Louis, Missouri, 63110, United States