Experimental lymphoma drug IPH6501 tested in early trial – but study halted

NCT ID NCT06088654

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tested an experimental drug called IPH6501 in 23 people with certain types of Non-Hodgkin lymphoma that had returned or stopped responding to prior treatments. The goal was to check safety and find the right dose, while also looking for signs that the drug shrinks tumors. The study was terminated early, so results are limited and it is unclear if the drug will move forward.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

IPH6501 (an experimental drug that targets CD20 on cancer cells)

What this could lead to

If it works, this could point toward a new treatment option for people with certain types of Non-Hodgkin lymphoma that have not responded to other therapies.

What could go wrong

This is a very early (first-in-human) trial that was terminated, so results are limited. The drug may not prove effective or safe in larger studies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diffuse large B-cell lymphoma follicular lymphoma high grade B-cell lymphoma mantle cell lymphoma marginal zone lymphoma non-Hodgkin lymphoma primary mediastinal large B-cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Austin Health

    Heidelberg, Australia

  • Cedars Sinai

    Los Angeles, California, 90048, United States

  • Centre Hospitalier Regional Universitaire de Lille

    Lille, France

  • Centre Hospitalier Universitaire de Nantes

    Nantes, France

  • City of Hope

    Duarte, California, 91010, United States

  • Hospices Civils de Lyon

    Lyon, 69002, France

  • Hôpital de la Coception

    Marseille, 13005, France

  • Icahn School Of Medicine At Mount Sinai

    New York, New York, 10029, United States

  • Institute Bergonie

    Bordeaux, France

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Monash Health

    Clayton, Victoria, 3168, Australia

  • Peninsula Private Hospital

    Frankston, Victoria, 3910, Australia

  • Siteman Cancer Center

    St Louis, Missouri, 63110, United States

  • Wollongong Private Hospital

    Wollongong, New South Wales, 2500, Australia