Off-the-Shelf cell therapy takes aim at tough blood cancers
NCT ID NCT07316907
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early study tests a new treatment for people with B-cell blood cancers that have come back or not responded to standard therapy. The treatment uses donor immune cells (CAR-T cells) designed to find and attack cancer cells. The main goal is to check if it's safe, with a small group of 12 participants.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- allogenic CD19-targeted CAR-T cells (19UCART)
- What this could lead to
- If it works, this could point toward a ready-made, off-the-shelf cell therapy for hard-to-treat blood cancers, reducing the need for patient-specific treatments.
- What could go wrong
- This is a very early Phase 1 trial with only 12 patients, so safety and effectiveness are far from proven. CAR-T therapy can cause severe side effects like cytokine release syndrome.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Affiliated Hospital of Jiangsu University
Zhenjiang, Jiangsu, 212001, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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