Off-the-Shelf cell therapy takes aim at tough blood cancers

NCT ID NCT07316907

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early study tests a new treatment for people with B-cell blood cancers that have come back or not responded to standard therapy. The treatment uses donor immune cells (CAR-T cells) designed to find and attack cancer cells. The main goal is to check if it's safe, with a small group of 12 participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

allogenic CD19-targeted CAR-T cells (19UCART)

What this could lead to

If it works, this could point toward a ready-made, off-the-shelf cell therapy for hard-to-treat blood cancers, reducing the need for patient-specific treatments.

What could go wrong

This is a very early Phase 1 trial with only 12 patients, so safety and effectiveness are far from proven. CAR-T therapy can cause severe side effects like cytokine release syndrome.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

B-cell childhood acute lymphoblastic leukemia B-cell neoplasm chronic lymphocytic leukemia/small lymphocytic lymphoma diffuse large B-cell lymphoma follicular lymphoma hematopoietic and lymphoid system neoplasm lymphoma mantle cell lymphoma marginal zone lymphoma Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Affiliated Hospital of Jiangsu University

    Zhenjiang, Jiangsu, 212001, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact