New CAR-T therapy aims to wipe out hidden lymphoma cells before they return

NCT ID NCT07443137

First seen Mar 09, 2026 · Last updated May 07, 2026 · Updated 4 times

Summary

This early-phase trial tests a personalized cell therapy called rapcabtagene autoleucel (YTB323) in 20 adults with large B-cell lymphoma who still have tiny amounts of cancer detectable after their first standard treatment. The goal is to see if the therapy can turn those leftover cancer signals negative, potentially lowering the risk of relapse. Participants must have high-risk disease and positive minimal residual disease (MRD) to join.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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