DEPRESSION
Clinical trials for DEPRESSION explained in plain language.
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Talking through the pain: group therapy offers hope for chronic pelvic pain
Symptom relief TerminatedThis study looked at whether a group therapy program could help women with chronic pelvic or belly pain feel better. The therapy focused on the mind and body together. Only 8 women took part, and the study was stopped early, so results are limited.
Matched conditions: DEPRESSION
Sponsor: Swiss Paraplegic Research, Nottwil • Aim: Symptom relief
Last updated May 17, 2026 19:24 UTC
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Mindfulness may ease anxiety for heart device patients
Symptom relief TerminatedThis study looked at whether a mindfulness-based program could help people with implanted heart devices (like pacemakers or defibrillators) feel less stressed, anxious, or depressed. About 34 adults who recently got such a device and had high anxiety or depression scores took par…
Matched conditions: DEPRESSION
Phase: NA • Sponsor: Chien Chih-Yin • Aim: Symptom relief
Last updated May 17, 2026 19:23 UTC
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Cancer depression app study ends early with just one participant
Symptom relief TerminatedThis study aimed to see if a mental health app could help head and neck cancer survivors with depression. Participants would use the app for 6 weeks and fill out surveys. However, the study was stopped early and only one person enrolled, so no meaningful results were obtained.
Matched conditions: DEPRESSION
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Symptom relief
Last updated May 17, 2026 19:20 UTC
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New depression pill shows promise in early trial
Symptom relief TerminatedThis study tested a new drug called REL-1017 as an extra treatment for people with major depression who didn't get enough help from standard antidepressants. The trial was stopped early after enrolling 27 adults. Researchers measured changes in depression symptoms using a standar…
Matched conditions: DEPRESSION
Phase: PHASE3 • Sponsor: Levomecor Inc. • Aim: Symptom relief
Last updated May 17, 2026 19:12 UTC
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Phone-Based therapy shows promise for depression, but study cut short
Symptom relief TerminatedThis study tested a program called Bounce Back, where people with mild to moderate depression get a self-help workbook and support from a trained coach over the phone. The goal was to see if this approach works better than usual care from a doctor. Only 20 people took part before…
Matched conditions: DEPRESSION
Phase: NA • Sponsor: University of British Columbia • Aim: Symptom relief
Last updated May 13, 2026 16:00 UTC
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Can tech boost depression treatment in cancer care?
Symptom relief TerminatedThis study looked at whether adding technology to collaborative care management helps cancer patients with depression. It involved 297 adults receiving cancer treatment at urban and rural centers. The goal was to see if tech-enhanced care improves treatment engagement and reduces…
Matched conditions: DEPRESSION
Phase: NA • Sponsor: University of Washington • Aim: Symptom relief
Last updated May 11, 2026 20:50 UTC
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Depression drug trial halted mid-study
Symptom relief TerminatedThis study tested whether adding a daily pill called REL-1017 to a person's usual antidepressant could better relieve major depression symptoms. About 236 adults with depression that wasn't fully controlled by their current medication took either REL-1017 or a placebo. The trial …
Matched conditions: DEPRESSION
Phase: PHASE3 • Sponsor: Levomecor Inc. • Aim: Symptom relief
Last updated May 11, 2026 20:38 UTC
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Perimenopause depression study halted after just 2 volunteers
Knowledge-focused TerminatedThis study aimed to understand how a natural brain chemical called allopregnanolone influences depression in women going through perimenopause. Researchers planned to measure changes in mood and thinking patterns. However, the study was stopped early and only enrolled 2 participa…
Matched conditions: DEPRESSION
Phase: PHASE4 • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated May 17, 2026 19:23 UTC
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Can talking about health help people with mental illness avoid heart problems?
Knowledge-focused TerminatedThis study followed 167 adults in primary care who had mental health issues like anxiety, depression, or sleep problems. Researchers used health conversations and a blood test to track lifestyle changes and heart risks over up to 20 years. The goal was to see if these tools could…
Matched conditions: DEPRESSION
Phase: NA • Sponsor: Region Skane • Aim: Knowledge-focused
Last updated May 17, 2026 19:23 UTC
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LGBTQ school support study halted early
Knowledge-focused TerminatedThis study aimed to see if a school-wide program could help LGBTQ high school students cope with stress, anxiety, depression, and bullying. About 228 students from 24 high schools took part. The program was tested but the study was stopped before completion, so we don't have full…
Matched conditions: DEPRESSION
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated May 17, 2026 19:21 UTC
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New program aims to help moms after preterm birth, but study cut short
Knowledge-focused TerminatedThis study tested a care coordination program for women who recently had a preterm baby. The goal was to see if the program was practical and well-received. Only 13 women enrolled before the study ended early. The results will help improve future support for mothers and babies.
Matched conditions: DEPRESSION
Phase: NA • Sponsor: Children's Hospital of Philadelphia • Aim: Knowledge-focused
Last updated May 11, 2026 20:38 UTC
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Can a simple guide help older adults with memory issues store guns more safely?
Knowledge-focused TerminatedThis small pilot study looked at whether a decision aid could help older adults with early dementia or depression think about safer firearm storage. Only 5 people took part, and the study was ended early. The goal was to see if the tool was easy to use and helpful, not to prove i…
Matched conditions: DEPRESSION
Phase: NA • Sponsor: University of Washington • Aim: Knowledge-focused
Last updated May 08, 2026 12:03 UTC
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Teen depression study asks: can writing online help?
Knowledge-focused TerminatedThis study looked at whether teens aged 14 to 21 with mild depression or anxiety would use a website to write articles. Researchers wanted to see if the approach was practical and acceptable. The study was stopped early, so results are limited.
Matched conditions: DEPRESSION
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated May 07, 2026 18:41 UTC