DEPRESSION
Clinical trials for DEPRESSION explained in plain language.
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Schools test program to protect LGBTQ youth from bullying and mental health crisis
Disease control TerminatedThis study tested a two-part school program designed to improve mental health for LGBTQ high school students. The program combined group sessions where youth could build coping skills with school-wide efforts to create a more supportive environment. Researchers aimed to see if th…
Matched conditions: DEPRESSION
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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New hope for stubborn depression? Add-On drug trial seeks better relief
Disease control TerminatedThis study tested whether a new drug called REL-1017 could help people with major depression who were still struggling despite taking standard antidepressant medication. Participants continued their usual medication and were randomly assigned to also take either REL-1017 or a pla…
Matched conditions: DEPRESSION
Phase: PHASE3 • Sponsor: Levomecor Inc. • Aim: Disease control
Last updated Mar 31, 2026 12:10 UTC
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New hope for Tough-to-Treat depression? trial tests Add-On pill
Disease control TerminatedThis study tested whether a daily pill called REL-1017 could help people with major depression who weren't getting enough relief from their current antidepressant. Participants took either the new pill or a placebo (sugar pill) for four weeks while continuing their regular medica…
Matched conditions: DEPRESSION
Phase: PHASE3 • Sponsor: Levomecor Inc. • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Pilot program aims to help moms after early births
Disease control TerminatedThis small study tested whether care coordination and motivational interviewing could help women after preterm births get needed follow-up care and address health behaviors like tobacco use and contraception. Researchers worked with 13 women who had Medicaid insurance and recentl…
Matched conditions: DEPRESSION
Phase: NA • Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated Mar 18, 2026 14:40 UTC
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Mind-Body group therapy tested for Women's chronic pain
Symptom relief TerminatedThis study tested a 12-session group therapy program designed to help women manage chronic pelvic and abdominal pain. The program combined psychotherapy and physiotherapy, focusing on the physical, psychological, and social aspects of pain. Researchers measured changes in pain, q…
Matched conditions: DEPRESSION
Sponsor: Swiss Paraplegic Research, Nottwil • Aim: Symptom relief
Last updated Mar 24, 2026 12:02 UTC
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App aims to ease depression for cancer survivors, but study stops early
Symptom relief TerminatedThis study aimed to test a smartphone app designed to help head and neck cancer survivors manage symptoms of depression. Participants were asked to use the mental health app for six weeks and complete surveys. The study was terminated early after enrolling only one person, so its…
Matched conditions: DEPRESSION
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Symptom relief
Last updated Mar 24, 2026 12:02 UTC
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Can teens help each other fight depression? a small study investigates
Knowledge-focused TerminatedThis study aimed to test whether a peer support program, where young people write and share articles about mental health, is a practical and acceptable approach to help with depression. It involved 12 participants aged 14-21 who reported mild depression or anxiety symptoms. The m…
Matched conditions: DEPRESSION
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated Apr 02, 2026 00:26 UTC
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Hormone probe for midlife depression
Knowledge-focused TerminatedThis study aimed to understand how changing levels of a natural hormone called allopregnanolone might contribute to depression in women during perimenopause. Researchers planned to give some participants a drug that increases this hormone to see how it affected their mood and bra…
Matched conditions: DEPRESSION
Phase: PHASE4 • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:35 UTC