New program aims to break the Pain-Depression cycle in older women

NCT ID NCT05619510

Terminated Symptom relief Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 12, 2026 · Updated 3 times

Summary

This study tested a program called PRIME for older women with chronic pain and depression who also have physical disabilities. Nine women took part in nurse-led goal-setting visits and group therapy sessions focused on acceptance and commitment. The goal was to see if this combined approach could reduce pain and improve mood without medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: PRIME Intervention (behavioral: nurse goal-setting visits and Acceptance Commitment Therapy group sessions)
What this could lead to: If it works, this could offer a non-drug way to help older women with disabilities manage both chronic pain and depression together.
What could go wrong: This was a very small pilot study with only 9 participants, so results may not apply to everyone. The program is time-intensive and may not work for all.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome Depression depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSION DEPRESSIVE SYMPTOMS DISABILITY PHYSICAL PAIN, CHRONIC

Contacts and locations

Locations

Johns Hopkins School of Nursing

Baltimore, Maryland, 21213, United States

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