New program aims to break the Pain-Depression cycle in older women

NCT ID NCT05619510

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a program called PRIME for older women with chronic pain and depression who also have physical disabilities. Nine women took part in nurse-led goal-setting visits and group therapy sessions focused on acceptance and commitment. The goal was to see if this combined approach could reduce pain and improve mood without medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

PRIME Intervention (behavioral: nurse goal-setting visits and Acceptance Commitment Therapy group sessions)

What this could lead to

If it works, this could offer a non-drug way to help older women with disabilities manage both chronic pain and depression together.

What could go wrong

This was a very small pilot study with only 9 participants, so results may not apply to everyone. The program is time-intensive and may not work for all.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome Depression depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Johns Hopkins School of Nursing

    Baltimore, Maryland, 21213, United States