CUTANEOUS MELANOMA

This study is testing if giving an immunotherapy drug called atezolizumab before surgery is safe for people with high-risk skin melanoma that hasn't spread. The drug aims to help the patient's own immune system fight the cancer, potentially lowering the chance of it coming back a…

This study is testing an experimental virus therapy called RP1, both alone and combined with an immunotherapy drug (nivolumab), for people with advanced solid tumors that have stopped responding to standard treatments. The trial aims to find the safest and most effective dose whi…

This small, early-stage study is testing if doing 30 minutes of moderate exercise right before standard immunotherapy can help the treatment work better against certain skin cancers. Researchers will enroll 22 adults with melanoma, squamous cell carcinoma, or Merkel cell carcinom…

This study is testing if a shorter, one-year course of pembrolizumab immunotherapy works as well as the standard two-year course for people with advanced melanoma that has spread or returned. It aims to make this effective treatment more accessible and affordable within Brazil's …

This is an early-stage study to test the safety and find the right dose of a new drug called PF-08046049/SGN-BB228. It is for adults with advanced solid tumors, including melanoma, lung, colorectal, pancreatic cancer, or mesothelioma, that have stopped responding to standard trea…

This is an early-stage study to find a safe dose of a new drug called KFA115, given alone or with an existing immunotherapy (pembrolizumab), for people with advanced cancers that have stopped responding to standard treatments. The main goal is to check for side effects and determ…

This study is testing a new drug called acasunlimab, given alone or together with the cancer drug pembrolizumab, for people with advanced skin melanoma that has continued to grow despite prior immunotherapy. The main goal is to see if the treatment can shrink tumors and is safe. …

This early-stage study is testing a personalized treatment called TBio-4101 for people with advanced melanoma that hasn't responded to standard therapies. Doctors take immune cells from a patient's tumor, grow them in large numbers in a lab, and then infuse them back into the pat…

This early-stage study is testing the safety of a new, personalized vaccine designed to teach the immune system to attack a patient's specific melanoma. The vaccine is given alongside two approved immunotherapy drugs. The main goal is to find a safe dose for a new way of giving o…

This study is testing whether photos taken with smartphone apps and special imaging devices can be as good as a visit to a dermatologist for finding melanoma early. Researchers are comparing three portable imaging systems to see how accurately they can identify suspicious moles t…