New cancer drug WTX-330 enters human testing for advanced tumors

NCT ID NCT06939283

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests an experimental drug called WTX-330 in 100 adults with advanced solid tumors or non-Hodgkin lymphoma that have not responded to standard treatments. The trial has two parts: first, finding the safest dose and schedule, then expanding to see how well the drug works against the cancer. Researchers will monitor side effects, tumor shrinkage, and survival.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
WTX-330
What this could lead to
If it works, this could point toward a new treatment option for people with advanced cancers or lymphoma that have not responded to standard therapies.
What could go wrong
This is an early, small trial (100 participants) focused on safety and dosing, so it is uncertain whether WTX-330 will effectively shrink tumors or improve survival. Side effects are possible and being closely monitored.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Emory Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

  • HonorHealth Research Institute

    Scottsdale, Arizona, 85258, United States

  • Indiana University Melvin and Bren Simon Comprehensive Cancer Center

    Indianapolis, Indiana, 46202, United States

  • NEXT Oncology

    San Antonio, Texas, 78229, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

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