New drug aims to boost immune system against advanced cancers

NCT ID NCT04328844

First seen Jun 27, 2026 · Last updated Jul 09, 2026 · Updated 2 times

Summary

This early-stage study tests a new drug called IOA-244 in about 210 adults with advanced or metastatic cancers like lung cancer, melanoma, and lymphoma. The main goal is to see if the drug is safe and tolerable, both alone and combined with other treatments. Researchers also check how the drug affects the body's immune response against tumors.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beatson West of Scotland Cancer Centre

    Glasgow, G12 0YN, United Kingdom

  • Humanitas Research Hospital

    Rozzano, Milan, 20089, Italy

  • Medical Oncology and Immunotherapy Unit, University Hospital of Siena

    Siena, 53100, Italy

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