New cancer antibody enters human testing
NCT ID NCT05378425
First seen Nov 01, 2025 · Last updated Apr 21, 2026 · Updated 22 times
Summary
This is the first study in people testing a new antibody drug called NTX-1088, which targets a protein found on many cancer cells. The trial will test the safety of NTX-1088 given alone and in combination with an existing immunotherapy drug (pembrolizumab) in 90 patients with advanced solid tumors that have spread or cannot be removed by surgery. The main goals are to find safe doses and understand how the body handles the drug.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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City of Hope
RECRUITINGDuarte, California, 91010, United States
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Hadassah Medical Center
RECRUITINGJerusalem, 9574425, Israel
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Maria Skłodowska-Curie National Research Institute of Oncology
NOT_YET_RECRUITINGWarsaw, Poland
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Ochsner Clinic Foundation
RECRUITINGNew Orleans, Louisiana, 70121, United States
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Sheba Medical Center
RECRUITINGRamat Gan, 5262131, Israel
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The University of Texas MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact
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Conditions
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