Pedaling against cancer: exercise may boost immunotherapy

NCT ID NCT06008977

Ongoing Knowledge-focused Sponsor: AdventHealth Translational Research Institute Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This small pilot study is testing whether a 30-minute stationary bike ride on the same day as immunotherapy can help the treatment work better for people with skin cancers like melanoma. The study involves 12 patients and focuses on whether this exercise plan is practical and safe. Researchers will also look at early signs of cancer response, but the main goal is to gather information for larger future studies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: supervised stationary bike exercise
What this could lead to: If it works, this could point toward a simple way to improve how well immunotherapy works for skin cancer patients.
What could go wrong: This is a very small pilot study with only 12 people, so results may not apply widely. It is testing feasibility, not yet proving effectiveness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cutaneous melanoma cutaneous neuroendocrine carcinoma melanoma skin squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CUTANEOUS MELANOMA CUTANEOUS SQUAMOUS CELL CARCINOMA MERKEL CELL CARCINOMA

Contacts and locations

Locations

AdventHealth Translational Research Institute

Orlando, Florida, 32804, United States

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