Tailor-Made vaccine takes on advanced melanoma in early trial
NCT ID NCT03929029
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tests a personalized vaccine (NeoVax) made from a patient's own tumor mutations, given alongside two immunotherapy drugs (nivolumab and ipilimumab) for advanced melanoma that cannot be surgically removed. The main goal is to check safety and find the right dose, with a secondary focus on whether the combination shrinks tumors. Only 11 participants with cutaneous melanoma are enrolled, and those with other melanoma types are excluded.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Other studies related to the condition(s) this trial covers.
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