New drug combo targets tough cancers in early trial

NCT ID NCT03891953

First seen Nov 10, 2025 · Last updated May 13, 2026 · Updated 21 times

Summary

This early-phase study tests a new drug (DKY709) alone or with another drug (PDR001) in people with advanced solid tumors like lung cancer, melanoma, and others that have stopped responding to standard treatments. The main goal is to check safety and find the right dose. About 98 adults will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Novartis Investigative Site

    Dresden, Saxony, 01307, Germany

  • Novartis Investigative Site

    Essen, 45147, Germany

  • Novartis Investigative Site

    Hong Kong, 999077, Hong Kong

  • Novartis Investigative Site

    Chuo Ku, Tokyo, 1040045, Japan

  • Novartis Investigative Site

    Barcelona, 08035, Spain

  • Novartis Investigative Site

    Taipei, 10002, Taiwan

  • Sarah Cannon Research Institute

    Nashville, Tennessee, 37203, United States

Conditions

Explore the condition pages connected to this study.