CROHN'S DISEASE
Clinical trials for CROHN'S DISEASE explained in plain language.
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Ancient herbal formula tested for modern Crohn's disease
Disease control OngoingThis early-stage study is testing the safety and tolerability of an oral herbal formula called E-B-FAHF-2 in adults with mild-to-moderate Crohn's disease. The goal is to see if this concentrated plant-based medicine can safely help maintain remission, filling a gap where few appr…
Matched conditions: CROHN'S DISEASE
Phase: PHASE1 • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Stem cell shots tested for debilitating Crohn's complications
Disease control TerminatedThis was an early, small safety study to test injections of donor stem cells into painful, hard-to-heal fistulas in people with Crohn's disease. The goal was to see if the treatment was safe and if it could help close these fistulas and improve patients' quality of life. The tria…
Matched conditions: CROHN'S DISEASE
Phase: PHASE1 • Sponsor: Joshua M Hare • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Real-World watch: tracking a Crohn's disease Drug's Long-Term performance
Disease control OngoingThis study is observing patients with moderate to severe Crohn's disease who are already being treated with the drug Entyvio (vedolizumab) in their regular doctor's care. The main goal is to collect long-term information on the drug's safety and how well it works to control the d…
Matched conditions: CROHN'S DISEASE
Sponsor: Takeda • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New Crohn's treatment shows promise in major Long-Term trial
Disease control OngoingThis study is testing the long-term effectiveness and safety of the drug mirikizumab for people with Crohn's disease. It follows nearly 1,000 patients who completed earlier studies of the same medication. Researchers are measuring whether the drug continues to reduce intestinal i…
Matched conditions: CROHN'S DISEASE
Phase: PHASE3 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New drug trial aims to tame debilitating Crohn's disease
Disease control OngoingThis large clinical trial is testing whether the medication guselkumab can help people with moderate to severe Crohn's disease. It involves over 1,400 participants and will measure if the drug reduces symptoms and improves gut healing over nearly a year. The study compares guselk…
Matched conditions: CROHN'S DISEASE
Phase: PHASE2, PHASE3 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated Mar 30, 2026 14:27 UTC
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New Two-Drug attack on Crohn's disease enters Mid-Stage testing
Disease control OngoingThis study is testing whether combining two existing drugs, guselkumab and golimumab, is better at controlling Crohn's disease than using either drug alone. It involves about 700 adults with moderate to severe Crohn's disease. The main goal is to see if the combination leads to f…
Matched conditions: CROHN'S DISEASE
Phase: PHASE2 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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New shot aims to tame debilitating gut disease
Disease control OngoingThis study is testing whether an injectable medication called risankizumab can help control symptoms and reduce gut inflammation in adults with moderate to severe Crohn's disease. Participants will receive either the active drug or a placebo injection for up to 24 weeks, followed…
Matched conditions: CROHN'S DISEASE
Phase: PHASE3 • Sponsor: AbbVie • Aim: Disease control
Last updated Mar 23, 2026 15:17 UTC
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Can changing your diet calm Crohn's and colitis flares?
Disease control OngoingThis study is testing whether two special diets can help people with active Crohn's disease or ulcerative colitis. Forty adults will follow either a partial liquid elemental diet or a specific carbohydrate diet for six weeks. Researchers will check if the diets reduce gut inflamm…
Matched conditions: CROHN'S DISEASE
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Mar 10, 2026 12:53 UTC
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Massive 20-Year study to track thousands of kids with Crohn's and colitis
Knowledge-focused OngoingThis study is collecting long-term health information from nearly 5,000 children and teenagers with Crohn's disease, ulcerative colitis, or other inflammatory bowel diseases. Researchers will follow participants for up to 20 years to understand the safety of treatments and how th…
Matched conditions: CROHN'S DISEASE
Sponsor: Janssen Biotech, Inc. • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Massive 15,000-Patient study aims to map the Real-World journey of IBD
Knowledge-focused OngoingThis study is creating a large, long-term registry of patients with Crohn's disease or ulcerative colitis to learn how these conditions behave and how treatments perform in everyday clinic settings. It will follow 15,000 adults and children (age 2+) for five years, collecting inf…
Matched conditions: CROHN'S DISEASE
Sponsor: Target PharmaSolutions, Inc. • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Brazilian IBD treatment patterns under review
Knowledge-focused OngoingThis study is collecting information about how Brazilian patients with Crohn's disease or ulcerative colitis use the medication vedolizumab. Researchers are reviewing existing treatment records from about 1006 patients to understand how long they stay on treatment and what outcom…
Matched conditions: CROHN'S DISEASE
Sponsor: Takeda • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Can a simple tool predict your Crohn's disease future?
Knowledge-focused OngoingThis study is observing how a new online tool, called CDPATH™, is used in regular doctor's offices. The tool estimates an adult patient's risk of developing Crohn's disease complications within the next three years. Researchers are enrolling about 200 recently diagnosed patients …
Matched conditions: CROHN'S DISEASE
Phase: PHASE4 • Sponsor: Takeda • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC