CROHN'S DISEASE

This study tested whether a web-based monitoring system could help people with complex inflammatory bowel disease (like Crohn's or colitis) stay in remission as well as standard clinic visits. 290 adults in Spain who were already taking strong medications for their condition were…

This study observed adults with moderate to severe Crohn's disease who started treatment with the drug vedolizumab in real-world clinic settings. Researchers followed 72 patients for 18 months to see if the treatment could lead to complete remission—meaning no symptoms, normal bl…

This study tested whether stem cell infusions could help people with moderate-to-severe Crohn's disease who hadn't responded to standard medications. 330 participants received either stem cells or a placebo through four IV treatments over two weeks. The goal was to see if the ste…

This study tested whether an infusion of donor stem cells could help people with moderate-to-severe Crohn's disease who don't respond to standard treatments. It focused on patients who had already shown some improvement from the cells in a previous trial, checking how long that b…

This study observed patients in China with moderate to severe Crohn's disease who were already prescribed the medication Humira (adalimumab). For one year, researchers tracked the drug's safety by recording any serious side effects and measured its effectiveness by seeing how man…

This study tested whether regularly checking the level of anti-TNF drugs in a patient's blood helps manage Crohn's disease and ulcerative colitis more effectively. 260 patients were split into two groups: one where doctors used these blood test results to adjust treatment, and on…

This study looked at whether patients could safely switch from the brand-name drug Remicade to a very similar, lower-cost version called Inflectra. It involved 262 patients at a Paris hospital who were already using Remicade for conditions like rheumatoid arthritis or Crohn's dis…

This study monitored Korean adults with moderate to severe ulcerative colitis or Crohn's disease who were prescribed the approved drug upadacitinib (RINVOQ) by their doctor. The goal was to collect real-world information on the drug's safety and how well it controls disease sympt…

This study tested whether doubling the dose of the medication TA-650 could help patients with Crohn's disease who weren't getting enough relief from the standard dose. It involved 39 adults whose symptoms returned despite regular treatment. Researchers measured changes in disease…

This study tested the safety of giving additional stem cell infusions to people with moderate-to-severe Crohn's disease who had already received an initial round of treatment. The 73 participants received three extra infusions over several months to see if continuing treatment wa…

This study aimed to understand the long-term safety of a medication called vedolizumab in children and teenagers with ulcerative colitis or Crohn's disease. It followed 59 young participants who had already responded to the drug in a previous trial, monitoring them for side effec…

This study observed patients with Crohn's disease or ulcerative colitis in Poland who were receiving vedolizumab treatment, either by IV infusion or a newer under-the-skin injection. Researchers tracked which treatment method patients stayed on longer and why some switched or sto…

This study aimed to understand if Crohn's disease is different in people who develop it as children versus older adults by comparing their gut bacteria. Researchers analyzed stool samples from 214 participants, including patients and healthy controls, to look for patterns linked …