New study aims to pinpoint fastest Crohn's symptom relief

NCT ID NCT06249555

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 300 adults with Crohn's disease who are starting standard treatments like vedolizumab or IL-23 blockers. Researchers will track how quickly patients feel improvements in pain, fatigue, and daily functioning using simple questionnaires. The goal is to better understand when these therapies start working, helping guide future treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

vedolizumab, ustekinumab, risankizumab, guselkumab, mirikizumab

What this could lead to

If successful, this study could help doctors predict which Crohn's treatment works fastest for each patient, improving personalized care.

What could go wrong

This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Crohn disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • ABP Research Services Corp.

    RECRUITING

    Oakville, Ontario, L6L5L7, Canada

    Contact Email: •••••@•••••

    Contact

  • Alimentiv

    RECRUITING

    London, Ontario, N6Z5B6, Canada

    Contact

  • Brigham and Women's Hospital

    RECRUITING

    Chestnut Hill, Massachusetts, 02467, United States

    Contact Email: •••••@•••••

    Contact

  • Cleveland Clinic Foundation

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact

    Contact Email: •••••@•••••

  • Digestive and Liver Center of Florida

    WITHDRAWN

    Kissimmee, Florida, 34741, United States

  • GI Alliance - Bellevue - Washington Gastroenterology

    RECRUITING

    Bellevue, Washington, 98004, United States

    Contact Email: •••••@•••••

    Contact

  • GI Alliance - Sun City

    RECRUITING

    Sun City, Arizona, 85351, United States

    Contact Email: •••••@•••••

    Contact

  • GI Alliance Research Fort Worth

    RECRUITING

    Fort Worth, Texas, 76104, United States

    Contact Email: •••••@•••••

    Contact

  • GI Alliance Research Mansfield

    RECRUITING

    Mansfield, Texas, 76063, United States

    Contact Email: •••••@•••••

    Contact

  • GNRR Digestive Clinics and Research Center

    RECRUITING

    Brampton, Ontario, L6S0E2, Canada

    Contact Email: •••••@•••••

    Contact

  • London Health Sciences Centre

    RECRUITING

    London, Ontario, N6A5A5, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • McMaster University Medical Center

    RECRUITING

    Hamilton, Ontatrio, L8N 3Z5, Canada

    Contact Email: •••••@•••••

    Contact

  • Montreal General Hospital

    RECRUITING

    Montreal, Quebec, H3G1A4, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Northwestern University

    RECRUITING

    Evanston, Illinois, 60611, United States

    Contact Email: •••••@•••••

    Contact

  • OR Clinic - East - GI

    RECRUITING

    Portland, Oregon, 97220, United States

    Contact Email: •••••@•••••

    Contact

  • Rajbir Rai Medicine Professional Corporation

    RECRUITING

    Oakville, Ontario, L6L4P7, Canada

    Contact Email: •••••@•••••

    Contact

  • Scarborough Center for Inflammatory Bowel Disease

    RECRUITING

    Scarborough Village, Ontario, M1B3V4, Canada

    Contact Email: •••••@•••••

    Contact

  • The Ottawa Hospital

    RECRUITING

    Ottawa, Ontario, K1H8L6, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Toronto Immune & Digestive Health Institute Inc.

    RECRUITING

    Toronto, Ontario, M6A3B4, Canada

    Contact Email: •••••@•••••

    Contact

  • University Medical Center New Orleans

    RECRUITING

    New Orleans, Louisiana, 70112, United States

    Contact Email: •••••@•••••

    Contact

  • University of Alberta

    RECRUITING

    Edmonton, Alberta, T6G2X8, Canada

    Contact Email: •••••@•••••

    Contact

  • University of British Columbia

    RECRUITING

    Vancouver, British Columbia, V6Z2K5, Canada

    Contact Email: •••••@•••••

    Contact

  • University of Iowa

    RECRUITING

    Iowa City, Iowa, 52242, United States

    Contact Email: •••••@•••••

    Contact

  • University of North Carolina

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

    Contact Email: •••••@•••••

    Contact

  • West GTA Research Inc.

    RECRUITING

    Mississauga, Ontario, L5M7N4, Canada

    Contact Email: •••••@•••••

    Contact