Ancient herbal mix gets a modern test for Crohn's

NCT ID NCT03992469

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-phase trial is testing whether an oral herbal formula called E-B-FAHF-2 is safe and tolerable for people with mild-to-moderate Crohn's disease. Only 7 adults will take either the herbal capsule or a placebo for a short time. The goal is to see if it reduces inflammation and helps maintain remission, with fewer pills needed than earlier versions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

E-B-FAHF-2 (a concentrated herbal formula)

What this could lead to

If it works, this could point toward a new treatment option for mild-to-moderate Crohn's disease that is easier to take than current therapies.

What could go wrong

This is a very early, small Phase 1 trial with only 7 participants, so results may not apply widely. The herbal formula may not prove effective or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Crohn disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States