COPD (CHRONIC OBSTRUCTIVE PULMONARY DISEASE)

This study compares three different dual bronchodilator inhalers (combining two types of long-acting medications) against a single medication inhaler (tiotropium) in people with COPD. The goal is to see which treatment best improves exercise endurance and lung function. About 100…

This study looks at whether a special training program for primary care doctors can help people with COPD take their medications more regularly. About 40 patients will be followed for 12 months to see if the training reduces flare-ups and improves how well doctors follow treatmen…

This study tests an experimental drug called JKN24011 in 215 people with moderate to severe COPD. The goal is to see if the drug can safely reduce the number of serious flare-ups compared to a placebo. Participants receive injections under the skin while continuing their usual CO…

This study tests a low-cost, equipment-free exercise program called Floor-Lift Series (FLS) for people with COPD who have trouble getting up from the floor. Sixteen participants will do progressive floor-to-stand movements for 9 weeks, with follow-up at 18 months. The goal is to …

This study was designed to see if elliptical exercise could improve walking ability and quality of life for people with chronic obstructive pulmonary disease (COPD). It planned to enroll patients who had already done pulmonary rehab for at least three months. However, the study w…

This small pilot study tests whether an inhaled drug called Treprostinil can reduce breathlessness and improve exercise ability in people with mild COPD. Twenty participants will undergo lung function tests, exercise tests, heart ultrasound, and CT scans over several visits. The …

This early-stage study tests a new drug called GB-0895 in adults with mild to moderate asthma or COPD. The main goal is to check if the drug is safe and how the body handles it. About 156 participants will receive either the drug or a placebo. This research is a first step to see…

This study looks at whether a Clinical Pilates exercise program can help people with mild (GOLD A) COPD. Researchers will measure changes in chest movement, lung function, physical performance, activity levels, sleep, and quality of life. About 38 participants will take part in t…

This study tests whether taking a probiotic supplement can help adults with COPD feel less short of breath and improve their daily symptoms. About 60 participants will take either a probiotic or a placebo for 16 weeks, and researchers will measure changes in breathing, lung funct…

This study follows 4,000 people with rheumatoid arthritis (ages 50-75) over 10 years to learn more about their risk for heart disease, lung problems, and mental health issues. Participants get a special heart CT scan, lung tests, and questionnaires. The goal is to better identify…

This study looks at whether people with COPD have less blood in their lungs than healthy people of the same age, sex, and height. Researchers will measure blood volume in the lungs and the whole body in 32 participants (16 with COPD and 16 healthy). The goal is to better understa…

This study looks at whether changing the wording of emails sent to GP practices can improve how they prescribe inhalers for COPD, a long-term lung condition. About 270 GP practices in West Yorkshire will get either a personalized email with feedback and tips, or a generic notice.…

This study looks at whether high-intensity interval training (HIIT) can help repair lung tissue in people with severe COPD who are waiting for lung volume reduction surgery. Twenty-four participants will be randomly assigned to either a HIIT exercise program or usual care. Resear…