COPD (CHRONIC OBSTRUCTIVE PULMONARY DISEASE)

This study compares three different dual bronchodilator inhalers (Anoro, Ultibro, Spiolto) against a single bronchodilator (Spiriva) in 100 people with COPD. The goal is to see which treatment improves exercise endurance the most. Each participant will try all four treatments for…

This study tests whether a special training program for primary care doctors can help people with COPD take their medications more regularly. The training includes updated COPD guidelines, inhaler technique workshops, and motivational interviewing. Researchers will compare medica…

This Phase 2 trial tests a new biologic drug called JKN24011 in 215 people with moderate to severe COPD. Participants receive either the drug or a placebo as a shot under the skin every four weeks. The main goal is to see if the drug can reduce the number of moderate or severe CO…

This early-stage study is testing an experimental drug called GB-0895 in 156 adults with mild-to-moderate asthma or COPD. The main goal is to check if the drug is safe and how the body processes it. Participants receive either the drug or a placebo as an injection under the skin.…

This study tests a new nurse-led counselling program designed to help people with stable COPD manage emotional distress. Fifteen outpatients will receive ten counselling sessions over three months. The main goal is to see if the program is feasible, not to prove it works. Researc…

This small pilot study tests whether an inhaled medication called Treprostinil can reduce breathlessness and improve exercise ability in people with mild COPD. Twenty participants will take either the drug or a placebo and undergo lung function tests, exercise tests, and imaging.…

This study is testing whether taking probiotic capsules daily for 16 weeks can reduce shortness of breath and improve lung function in people with COPD. Sixty adults with stable COPD will receive either the probiotic or a placebo. Researchers will measure changes in breathing, sy…

This study tests a low-cost, equipment-free exercise program for people with COPD who have trouble getting up from the floor. The program uses simple floor-to-stand movements done at home and with supervision for 9 weeks, with a check-up at 18 months. The goal is to see if this p…

This study tests whether an 8-week Clinical Pilates program can improve lung function, chest mobility, motor performance, sleep, and quality of life in 38 people with mild (Gold A) COPD. Participants will attend two 60-minute sessions per week using soft balls and elastic bands. …

This study looks at whether having a heart doctor check patients during a COPD flare-up helps find and treat hidden heart problems. 150 hospitalized adults with COPD are randomly assigned to see only a lung doctor or also a heart doctor. Researchers then track changes in heart tr…

This study looks at whether high-intensity interval training (HIIT) can help regenerate lung tissue in people with COPD who are waiting for lung volume reduction surgery. 24 participants will be randomly assigned to either a HIIT exercise program or no exercise. Researchers will …

This study compares 16 people with mild-to-moderate COPD to 16 healthy volunteers matched by age, sex, and height. Researchers measure blood volume in the lungs and the whole body to see if a smaller lung blood volume contributes to exercise problems. No treatment is given—the go…

This study was designed to test whether eccentric cycling (a type of exercise that focuses on lengthening muscles) could improve heart and lung fitness and quality of life in people with chronic obstructive pulmonary disease (COPD). The plan was to compare eccentric cycling to st…

This study will use advanced heart scans (coronary CT angiography) on 4,000 people with rheumatoid arthritis aged 50-75. The goal is to better understand why people with this condition have higher risks of heart attacks, strokes, and lung problems. Researchers will track particip…

This study tests whether personalized emails to GP practices can improve prescribing for COPD, a long-term lung condition. About 270 practices in West Yorkshire, UK, will receive either a generic or a tailored email alongside their regular feedback reports. The goal is to see if …