COPD (CHRONIC OBSTRUCTIVE PULMONARY DISEASE)

This early-stage study tests whether an oral probiotic called R-3750 is safe for people with mild to moderate COPD. About 27 adults will take the probiotic and be monitored for side effects. Researchers will also look for signs that the treatment might improve breathing and quali…

This study looks at whether using a non-invasive ventilator (BiPAP) at home can improve health in people with severe COPD who have high carbon dioxide levels. Forty adults with advanced COPD will use the machine nightly and be monitored for changes in blood gas levels, breathing …

This study tests an experimental drug called Hemay005 in 120 adults with moderate to severe COPD, a long-term lung disease that makes breathing difficult. The goal is to see if the drug can reduce lung inflammation and improve symptoms compared to a placebo or an existing medicat…

This study tests if a pharmacist-led mobile game can improve health in adults aged 50 and older with COPD. Participants use the game at home for 2 weeks with pharmacist support. The goal is to see if it helps with symptoms, inhaler use, and medication habits compared to usual car…

This study checks if a second round of a freezing spray treatment inside the lungs is safe for people with COPD and chronic bronchitis. It involves 10 adults who have already had this treatment once before. The main goal is to see if the procedure can be completed as planned and …

This study tests whether adding blood flow restriction to low-intensity aerobic exercise helps people with COPD more than standard pulmonary rehabilitation. 34 adults aged 40-80 with stable COPD will be split into two groups: one doing standard rehab, the other adding blood flow …

This study aims to see if long-term use of a BiPAP breathing support machine can improve the function of the diaphragm, the main breathing muscle, in people with advanced COPD. Researchers will follow 30 patients for a year, using ultrasound to measure the diaphragm and tracking …

This study tests a handheld device that measures carbon dioxide in your breath to diagnose asthma and COPD. Instead of forceful breathing tests, you just breathe normally for 75 seconds. The goal is to make diagnosis faster, easier, and more accessible, especially in community cl…

This study tests a mobile app called Respir'air BPCO designed to help people with COPD stay physically active after completing a pulmonary rehabilitation program. Researchers will compare two groups: one using the app plus usual care, and another receiving only usual care. The go…

This study looks at whether manual therapy (a type of hands-on treatment) can improve how people with COPD walk, including their step length and speed. Researchers will also check if it helps with balance, breathing, and quality of life. The study plans to include 40 adults aged …

This study tests a new treatment called Targeted Lung Denervation (TLD) for people with moderate to severe COPD. The procedure uses a catheter to calm overactive nerves in the lungs, aiming to reduce symptoms like breathlessness and prevent flare-ups. About 300 participants will …

This study looks at whether a pulmonary rehabilitation program for people with COPD can be done just one day a week instead of three, while still being effective. The goal is to make these programs easier to attend and more accessible. Researchers will measure walking ability, br…

This study tests if a gentle, non-invasive brain stimulation (NIBS) can improve memory and attention in people with COPD who have thinking problems. Twenty-four adults with stable COPD and mild cognitive issues will receive either real or fake stimulation for 20 minutes a day, 5 …

This study tests a digital, high-intensity breathing exercise program for people with moderate to severe COPD. The goal is to see if it improves lung function and the ability to exercise, like walking. Sixty participants aged 50-65 will use a device at home to strengthen their br…

This study tests a new training program to improve nurses' ability to teach patients with COPD how to use their inhalers correctly. 82 registered nurses in Hong Kong will attend a workshop and receive follow-up videos. The goal is to see if the training helps nurses master the co…

This study looks at how often urinary incontinence happens in women with COPD who are doing pulmonary rehabilitation. About 100 women aged 45 and older will take part. The goal is to measure leakage after exercise and see how it affects their quality of life, so doctors can bette…

This study will measure the quality of life of 71 adults with COPD who visit a hospital spirometry center in Kathmandu, Nepal. Researchers will use simple questionnaires to understand how breathing problems affect daily activities and overall well-being. The goal is to identify f…

This study looks at whether adding a heart evaluation to standard lung care helps people with mild-to-moderate COPD who also have heart disease or high heart risk. About 350 adults will be randomly assigned to get either the combined heart-lung check or usual lung care. Researche…

This study looks at how people with COPD and healthy volunteers experience shortness of breath. Researchers will use virtual reality, brain activity measurements, and a placebo device to better understand what causes breathlessness and how it can be influenced. The goal is to lea…