Could a vibrating mesh nebuliser ease breathing for COPD patients on ventilation?

NCT ID NCT06884228

First seen Jul 10, 2026 ยท Last updated Jul 10, 2026

Summary

This study tests whether a vibrating mesh nebuliser delivers bronchodilator medication more effectively than a standard jet nebuliser in people with COPD who use non-invasive ventilation at home. Researchers will measure breathing muscle activity, lung function, and breathlessness after each type of nebuliser. The goal is to see if the vibrating mesh device improves drug delivery and reduces the work of breathing.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Vibrating mesh nebulisation device
What this could lead to
If vibrating mesh nebulisation proves more effective, it could improve drug delivery and breathing comfort for COPD patients using non-invasive ventilation.
What could go wrong
This is a very small, early-stage study with only 12 participants, so results may not apply broadly. The intervention is a device, not a new drug, so the potential impact is limited.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Lane Fox Unit, St Thomas' Hospital, Guy's and St Thomas' NHS Foundation Trust

    London, SE1 7EH, United Kingdom

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