COLITIS, ULCERATIVE

This study is observing how well the drug guselkumab works for adults with moderate-to-severe Crohn's disease or ulcerative colitis in real-world UK clinics. It will track 220 patients to see if the treatment reduces symptoms, improves quality of life, and helps them stop using s…

This program provides special early access to the drug etrasimod for patients with severe ulcerative colitis who have no other treatment options. It is for individuals who have tried and failed at least three other available therapies or cannot tolerate them. The program allows d…

This study follows 400 people with Crohn's disease or ulcerative colitis who are starting treatment with guselkumab in real-world medical settings. The main goal is to see how well the drug controls symptoms like abdominal pain, diarrhea, and rectal bleeding, and to measure its i…

This study is checking the long-term safety of guselkumab in children who already benefited from it in previous studies. It includes 196 children with Crohn's disease, ulcerative colitis, or juvenile psoriatic arthritis. The main goal is to see if the drug remains safe when used …

This study aims to see how well the drug guselkumab works for people in China with moderate-to-severe ulcerative colitis, a chronic inflammatory bowel disease. It will follow 200 patients who are starting this type of medication for the first time, observing their symptoms, quali…

This study aims to see how well the medication etrasimod works for adults with moderate-to-severe ulcerative colitis in everyday, real-world settings. It will follow 300 patients for one year as they take the drug as part of their standard care. The main goal is to measure how ma…

This study aims to understand the long-term safety and effectiveness of the medication tulisokibart for people with moderate to severe Crohn's disease or ulcerative colitis. It's an extension study for 1,380 participants who previously benefited from tulisokibart in earlier trial…

This study is testing whether an oral medication called ozanimod can help children with moderate-to-severe ulcerative colitis achieve and maintain remission. It is for kids whose symptoms haven't improved enough with standard treatments. Researchers will measure how well the drug…

This is the first study to give a new drug called GSK4528287 to people. It aims to treat inflammatory bowel diseases like ulcerative colitis. Researchers will give single, increasing doses to 48 healthy volunteers to check for side effects, see how long the drug stays in the bloo…

This study is testing several long-acting antibody treatments, both alone and in combinations, for adults with moderate to severe ulcerative colitis. The goal is to see if these treatments can control the disease by reducing inflammation and symptoms. The trial will involve 645 p…

This study is testing whether a specific, sustainable diet can help people with active ulcerative colitis. Researchers want to see if this diet changes the bacteria in the gut, which could lead to less inflammation and fewer symptoms. The study is enrolling 20 adults with mild to…

This study is testing a new drug called SAR441566 to see if it can help control moderate-to-severe ulcerative colitis and put the disease into remission. About 204 adults who haven't gotten enough relief from standard or advanced treatments will receive either the drug or a place…

This study aims to compare the long-term safety of ustekinumab against other biologic drugs for adults with Crohn's disease or ulcerative colitis. Researchers will use existing military health records to track over 1,000 patients who are starting these treatments. The main goal i…

This large, late-stage study is testing a pill called icotrokinra to see if it can bring and keep ulcerative colitis under control. It will involve about 882 adults and teenagers whose current treatments aren't working well enough. The main goal is to see if the drug can put the …

This study is testing two dietary supplements to see if people with chronic diseases find them easy to take and stick with. It will also check if taking the supplements helps the body absorb more iron and zinc, which could improve quality of life. The study is enrolling 100 adult…

This study aims to understand why so many people with ulcerative colitis also have sleep problems. Researchers will observe 152 patients to see how poor sleep relates to their gut bacteria, brain activity, and disease severity. The goal is to gather knowledge about this connectio…

This study aims to find the best way to check for magnesium deficiency in people with gut diseases like Crohn's, colitis, or an ileostomy. Researchers will compare several different measurement methods, including blood tests, urine tests, and optional muscle biopsies, in 120 part…