New study tests biologic drug guselkumab for ulcerative colitis in chinese patients

NCT ID NCT07302360

Recruiting now Disease control Sponsor: Xian-Janssen Pharmaceutical Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 31, 2026 · Updated 4 times

Summary

This study follows 200 Chinese patients with moderate-to-severe ulcerative colitis who have never taken biologic drugs. They will receive guselkumab as part of their normal care. Researchers will measure changes in symptoms and quality of life over 48 weeks to see how well the drug works in everyday practice.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Guselkumab (a biologic medicine given by injection)
What this could lead to: If successful, this study could show that guselkumab is a safe and effective treatment option for ulcerative colitis in patients who have not used biologics before.
What could go wrong: This is an observational study, not a controlled trial, so results may be less definitive. It is also limited to Chinese patients, so findings may not apply to other populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLITIS, ULCERATIVE

Contacts and locations

Locations

Changzhou No 2 Peoples Hospital
RECRUITING

Changzhou, 213003, China
Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School
RECRUITING

Nanjing, 223800, China
Peking Union Medical College Hospital
RECRUITING

Beijing, 100006, China
Peking University People's Hospital
RECRUITING

Beijing, 100044, China
Sir Run Run Shaw Hospital Zhejiang University School of Medicine
RECRUITING

Hangzhou, 310018, China
The First Affiliated Hospital Sun Yat-Sen University
RECRUITING

Guangzhou, 510080, China
The Second Affiliated Hospital of Zhejiang University
RECRUITING

Hangzhou, 310009, China
The Second Hospital of Hebei Medical University
RECRUITING

Shijiazhuang, 050000, China
The Sixth Affiliated Hospital of Sun Yat-sen University
RECRUITING

Guangzhou, China
Tianjin Medical University General Hospital
RECRUITING

Tianjin, 300052, China

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