COLITIS, ULCERATIVE

This study tested a medicine called vedolizumab in 121 children with moderate to severe ulcerative colitis, a condition causing gut inflammation and pain. The goal was to see if the drug could bring about remission—meaning symptoms improve and the gut looks healthy on camera. Par…

This study tested an experimental drug called BI 655130 in 22 adults with mild-to-moderate ulcerative colitis who were already taking TNF inhibitor therapy. The goal was to see if adding BI 655130 could help heal the lining of the colon (mucosal healing) and improve symptoms. The…

This study looked at the long-term safety of a drug called spesolimab in 79 adults with moderate to severe ulcerative colitis who had already taken part in earlier studies. The main goal was to track side effects over time, and researchers also checked how many patients achieved …

This study tested a new medication, JNJ-77242113, in 252 adults with moderate to severe ulcerative colitis. The goal was to see if the drug could reduce symptoms like diarrhea and rectal bleeding better than a placebo. Participants took the drug or a placebo for 12 weeks, and doc…

This study looked at 688 people with ulcerative colitis or Crohn's disease who received Vedolizumab (Kynteles) as part of their normal care in South Korea. The main goal was to track side effects and see how many patients felt better after treatment. Vedolizumab helps control inf…

This study tested an experimental drug called MORF-057 in 39 adults with moderate-to-severe ulcerative colitis, a chronic inflammatory bowel disease. The goal was to see if the drug could reduce gut inflammation and improve symptoms over 12 weeks. Participants took the pill by mo…

This study tested a drug called spesolimab in 98 adults with moderate-to-severe ulcerative colitis who did not get better with previous biologic treatments. The goal was to see if the drug could reduce symptoms and inflammation, aiming for remission. The trial was completed and u…

This study tested a new drug called TEV-48574 in 290 adults with moderate to severe ulcerative colitis or Crohn's disease. The goal was to see if the drug could reduce inflammation and bring about remission after 14 weeks of treatment. Participants received one of two doses or a …

This study tested two doses of an oral medication called ozanimod in 198 Japanese adults with moderate-to-severe ulcerative colitis. The goal was to see if the drug could reduce symptoms like diarrhea and rectal bleeding better than a placebo. Participants took the drug daily for…

This study looked at physical fitness in 100 children aged 10-17 with chronic inflammatory bowel disease (like Crohn's or ulcerative colitis) and compared them to healthy children of the same age, size, and sex. Researchers measured things like heart-lung fitness, muscle strength…

This early study tested a new drug called BI 655130 in 8 adults with moderate to severe ulcerative colitis. The main goal was to see how the drug affects genes in the gut lining, not to prove it works as a treatment. Researchers also checked safety and signs of inflammation. Beca…

This study observed 92 adults with inflammatory bowel disease (Crohn's or ulcerative colitis) in Switzerland who were taking vedolizumab either as an IV infusion or a shot under the skin. Researchers tracked which route patients chose and why, and how long they stayed on treatmen…