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Real-World study confirms kynteles safety for IBD patients

NCT ID NCT04799496

Completed Disease control Sponsor: Takeda Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study monitored 688 people in South Korea with ulcerative colitis, Crohn's disease, or pouchitis who were treated with Kynteles (vedolizumab) as part of their normal care. The main goal was to track side effects, and researchers also looked at how many patients saw symptom improvement. The results help confirm the drug's safety and effectiveness in everyday practice.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Vedolizumab (Kynteles injection)

What this could lead to

If successful, this study confirms vedolizumab is safe and effective for managing ulcerative colitis, Crohn's disease, and pouchitis in routine care.

What could go wrong

This is a post-marketing surveillance study, not a new treatment test. It only observes real-world use, so it won't prove new benefits or cures.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Crohn disease inflammatory bowel disease pouchitis ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLITIS, ULCERATIVE CROHN DISEASE INFLAMMATORY BOWEL DISEASES

Contacts and locations

Locations

  • Asan Medical Center

    Seoul, 05505, South Korea

  • CHA University Bundang Medical Center

    Seongnam, 13496, South Korea

  • Chosun University Hospital

    Gwangju, 61453, South Korea

  • Chung-Ang University Hospital

    Seoul, 06973, South Korea

  • Chungbuk National University Hospital

    Cheongju-si, 28644, South Korea

  • Daegu Patima Hospital

    Daegu, 41199, South Korea

  • Dong-A University Hospital

    Busan, 49201, South Korea

  • DongGuk University International Hospital

    Ilsan, 10326, South Korea

  • Gangnam Severance Hospital

    Seoul, 06273, South Korea

  • Good Gang-An Hospital

    Busan, 48265, South Korea

  • Hallym Univ. Medical Center

    Chuncheon, 24253, South Korea

  • Hanyang University Medical Center

    Gyeonggi-do, 11923, South Korea

  • Ilsan Paik Hospital

    Ilsan, 10380, South Korea

  • Inje University Busan Paik Hospital

    Busan, 47392, South Korea

  • Inje University Haeundae Paik Hospital

    Busan, 48108, South Korea

  • Inje University Ilsan Paik Hospital

    Gyeonggi-do, 10380, South Korea

  • Inje University Sanggye Paik Hospital

    Seoul, 01757, South Korea

  • Jeonbuk National University Hospital

    Jeonju, 54907, South Korea

  • Kangbuk Samsung Hospital

    Seoul, 03181, South Korea

  • Kangwon National University Hospital

    Chuncheon, 24289, South Korea

  • Keimyung University Dongsan Hospital

    Daegu, 42601, South Korea

  • Koo Hospital

    Daegu, 42644, South Korea

  • Korea University Ansan Hospital

    Gyeonggi-do, 15355, South Korea

  • Kosin University Gospel Hospital

    Busan, 49267, South Korea

  • KyungHee University Hospital

    Seoul, 02447, South Korea

  • Kyunghee University Hospital at Gangdong

    Seoul, 05278, South Korea

  • Kyungpook National University Chilgok Hospital

    Daegu, 41404, South Korea

  • Kyungpook National University Hospital

    Daegu, 41404, South Korea

  • Nowon Eulji Medical Center, Eulji University

    Seoul, 01830, South Korea

  • Pusan National University Hospital

    Busan, 49241, South Korea

  • Pusan National University Yangsan Hospital

    Yangsan, 50612, South Korea

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Seoul National University Bundang Hospital

    Seongnam, 13620, South Korea

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • Seoul St.Mary's Hospital

    Seoul, 06591, South Korea

  • Severance Hospital

    Seoul, 03722, South Korea

  • Soon Chunhyang University Hospital Bucheon

    Bucheon-si, 14584, South Korea

  • Soonchunhyang University Cheonan Hospital

    Cheonan, 31151, South Korea

  • The Catholic University of Korea, Bucheon ST. Marys Hospital

    Gyeonggi-do, 14647, South Korea

  • The Catholic University of Korea, Daejeon ST. Mary's Hospital

    Daejeon, 34943, South Korea

  • Ulsan university Hospital

    Ulsan, 44033, South Korea

  • Wonju Severance Christian Hospital

    Wŏnju, 26426, South Korea

  • Yeungnam University Medical Center

    Daegu, 42415, South Korea