COLITIS, ULCERATIVE

This study aims to collect long-term safety information for children and teenagers (ages 2 to 18) who are receiving ustekinumab injections for Crohn's disease, ulcerative colitis, or psoriatic arthritis. It is an extension study for participants who benefited from the drug in a p…

This study is testing whether two different doses of an experimental medication called TEV-48574 can help control symptoms of moderate to severe Crohn's disease or ulcerative colitis over the long term. The medication is given as an injection under the skin every four weeks. The …

This study is testing a new oral drug called SAR443122 to see if it can help control ulcerative colitis in adults whose current treatments aren't working well enough. About 187 participants will receive either the new drug at one of three doses or a placebo for up to a year. The …

This study is testing whether an injectable medication called guselkumab can help control symptoms and heal the gut lining in adults with moderate to severe ulcerative colitis. About 418 participants will receive either the drug or a placebo injection to see if it leads to remiss…

This study is testing whether an existing drug called dupilumab can help control symptoms in adults with moderate-to-severe ulcerative colitis who have a specific immune pattern. About 68 participants will receive either the drug or a placebo for 52 weeks to see if it reduces gut…

This study is testing whether combining two existing drugs, guselkumab and golimumab, is more effective and safe than using either drug alone for treating moderate-to-severe ulcerative colitis. It involves about 577 adults whose condition hasn't improved enough with other advance…

This study is testing a medicine called guselkumab in children and teenagers with moderate to severe ulcerative colitis, a chronic inflammatory bowel disease. It aims to see if the drug can help control the disease, reduce symptoms like abdominal pain and bleeding, and improve gu…

This study is testing an investigational oral drug called MORF-057 to see if it can help control moderate to severe ulcerative colitis. It will compare three different doses against a placebo pill in about 280 adults who haven't gotten enough relief from standard treatments. The …

This study aims to determine the best treatment goal for people with active ulcerative colitis. Researchers are comparing three different targets: symptom relief alone, symptom relief plus healing seen during a colonoscopy, or achieving all of that plus microscopic healing of int…

This study is testing whether regular injections of a medication called golimumab can help children with moderate to severe ulcerative colitis achieve and maintain remission. It involves 84 young participants and measures how well the drug controls symptoms and heals the gut lini…

This study is testing whether acupuncture, when added to standard medications, can help children and teenagers with Crohn's disease or ulcerative colitis. It aims to see if the treatment reduces disease activity, lessens chronic pain, and improves overall quality of life. The tri…

This study is testing whether a health education program led by specialized nurses can help improve quality of life and reduce symptoms of anxiety and depression in adults living with a digestive ostomy after surgery. The program involves workshops and follow-up care for about 70…