New pill offers hope for kids with severe colitis

NCT ID NCT05076175

Recruiting now Disease control Sponsor: Bristol-Myers Squibb Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 2 times

Summary

This study tests an oral medication called ozanimod in children aged 12-17 with moderate-to-severe ulcerative colitis who haven't responded to standard treatments. The goal is to see if the drug can safely bring the disease into remission. About 120 participants will receive either ozanimod or a placebo to compare results.

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Conditions

The condition(s) this trial relates to.

ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLITIS, ULCERATIVE

Contacts and locations

Locations

Aichi Children's Health and Medical Center
RECRUITING

Ōbu, Aichi-ken, 474-8710, Japan
Barts Health NHS Trust
RECRUITING

London, London, City of, E1 1BB, United Kingdom
Birmingham Children's Hospital
RECRUITING

Birmingham, England, B4 6NH, United Kingdom
Boston Children's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States
CHU de Toulouse - Hôpital des Enfants
RECRUITING

Toulouse, Haute-Garonne, 31059, France
Cedars-Sinai Medical Center
RECRUITING

Los Angeles, California, 90048, United States
Centre Hospitalier Régional de la Citadelle
RECRUITING

Liège, 4000, Belgium
Centre Hospitalier Universitaire de Caen - Hôpital Côte de Nacre
RECRUITING

Caen, 14033, France
Centrum Zdrowia Dziecka w Warszawie
RECRUITING

Warsaw, Masovian Voivodeship, 04-746, Poland
Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44124, United States
Clinical Research Puerto Rico
RECRUITING

San Juan, 00909-1711, Puerto Rico
Columbia University Medical Center
RECRUITING

New York, New York, 10032, United States
Hiroshima University Hospital
RECRUITING

Hiroshima, 734-8551, Japan
Institute of Science Tokyo Hospital
RECRUITING

Bunkyo-Ku, Tokyo, 113-8519, Japan
Juntendo University Hospital
RECRUITING

Tokyo, 113-8431, Japan
King's College Hospital
RECRUITING

London, Greater London, SE5 9RS, United Kingdom
Komatsu Municipal Hospital
RECRUITING

Komatsu, Ishikawa-ken, 923-8560, Japan
Kurume University Hospital
RECRUITING

Kurume-shi, Fukuoka, 8300011, Japan
Local Institution
WITHDRAWN

Moscow, 119991, Russia
Local Institution
WITHDRAWN

Moskva, 119571, Russia
Local Institution - 0007
COMPLETED

Hartford, Connecticut, 06106, United States
Local Institution - 0013
WITHDRAWN

Gdansk, Pomeranian Voivodeship, 80-803, Poland
Local Institution - 0015
WITHDRAWN

Rzeszów, Podkarpackie Voivodeship, 35-302, Poland
Local Institution - 0016
COMPLETED

Atlanta, Georgia, 30342, United States
Local Institution - 0017
COMPLETED

Paris, 75015, France
Local Institution - 0022
COMPLETED

Bron, 69500, France
Local Institution - 0023
WITHDRAWN

New York, New York, 10065, United States
Local Institution - 0028
COMPLETED

New York, New York, 10029, United States
Local Institution - 0031
COMPLETED

Dresden, 01307, Germany
Local Institution - 0032
COMPLETED

München, Bavaria, 80337, Germany
Local Institution - 0037
COMPLETED

Milwaukee, Wisconsin, 53226, United States
Local Institution - 0041
WITHDRAWN

Phoenix, Arizona, 85016-7710, United States
Local Institution - 0042
COMPLETED

Springfield, Massachusetts, 01199, United States
Local Institution - 0044
COMPLETED

Madrid, Madrid, Comunidad de, 28009, Spain
Local Institution - 0045
COMPLETED

Hershey, Pennsylvania, 17033, United States
Local Institution - 0047
COMPLETED

Charlotte, North Carolina, 28203, United States
Local Institution - 0048
COMPLETED

Badalona, Barcelona [Barcelona], 08916, Spain
Local Institution - 0049
COMPLETED

Iowa City, Iowa, 52242, United States
Local Institution - 0050
WITHDRAWN

Madrid, 28046, Spain
Local Institution - 0051
COMPLETED

Esplugues de Llobregat, Barcelona [Barcelona], 08950, Spain
Local Institution - 0052
COMPLETED

Garden Grove, California, 92845, United States
Local Institution - 0056
COMPLETED

Brussels, 1090, Belgium
Local Institution - 0057
COMPLETED

Madrid, 28007, Spain
Local Institution - 0062
WITHDRAWN

Oklahoma City, Oklahoma, 73112, United States
Local Institution - 0063
NOT_YET_RECRUITING

Edegem, 2650, Belgium
Local Institution - 0064
COMPLETED

Washington D.C., District of Columbia, 20010, United States
Local Institution - 0071
WITHDRAWN

Liège, 4000, Belgium
Local Institution - 0073
WITHDRAWN

Paris, 75571, France
Local Institution - 0075
COMPLETED

Orlando, Florida, 32803, United States
Local Institution - 0076
WITHDRAWN

Brussels, Bruxelles-Capitale, Région de, 1090, Belgium
Local Institution - 0079
WITHDRAWN

Gdansk, Pomeranian Voivodeship, 80-803, Poland
Local Institution - 0082
NOT_YET_RECRUITING

Toronto, Ontario, M5G 1X8, Canada
Local Institution - 0083
WITHDRAWN

Hamilton, Ontario, L8N 3Z5, Canada
Local Institution - 0084
WITHDRAWN

Krakow, Lesser Poland Voivodeship, 30-663, Poland
Local Institution - 0086
WITHDRAWN

Murdoch, Western Australia, 6150, Australia
Local Institution - 0091
COMPLETED

Seattle, Washington, 98122, United States
Local Institution - 0092
COMPLETED

Lodz, Łódź Voivodeship, 91-738, Poland
Local Institution - 0093
COMPLETED

Detroit, Michigan, 48201, United States
Local Institution - 0099
NOT_YET_RECRUITING

Charleston, South Carolina, 29425, United States
Local Institution - 0100
NOT_YET_RECRUITING

Indianapolis, Indiana, 46202, United States
Local Institution - 0101
NOT_YET_RECRUITING

Park Ridge, Illinois, 60068, United States
Local Institution - 0103
NOT_YET_RECRUITING

Fort Worth, Texas, 76104, United States
Local Institution - 0104
NOT_YET_RECRUITING

Toronto, Ontario, M3M 0B2, Canada
Local Institution - 0105
NOT_YET_RECRUITING

London, Greater London, SW10 9NH, United Kingdom
Loma Linda University Health System
RECRUITING

Loma Linda, California, 92354, United States
Lucile Packard Children's Hospital
NOT_YET_RECRUITING

Palo Alto, California, 94304, United States
Maine Medical Partners
NOT_YET_RECRUITING

Portland, Maine, 04102, United States
Mayo Clinic in Rochester, Minnesota
RECRUITING

Rochester, Minnesota, 55905, United States
Monash Health
RECRUITING

Clayton, Victoria, 3168, Australia
MultiCare Health System
RECRUITING

Tacoma, Washington, 98405, United States
National Center for Child Health and Development
RECRUITING

Setagaya-ku, Tokyo, 1578535, Japan
Osaka Medical and Pharmaceutical University Hospital
RECRUITING

Takatsuki, Osaka, 569-8686, Japan
Rambam Health Care Campus
RECRUITING

Haifa, Northern District, 3109601, Israel
Saiseikai Yokohamashi Tobu Hospital
RECRUITING

Yokohama, Kanagawa, 2300012, Japan
Schneider Children's Medical Center
RECRUITING

Petah Tikva, Central District, 49202, Israel
Seattle Children's Hospital
RECRUITING

Seattle, Washington, 98105, United States
Shaare Zedek Medical Center
RECRUITING

Jerusalem, Jerusalem, 9013102, Israel
Texas Children's Hospital
RECRUITING

Houston, Texas, 77030, United States
The Children's Hospital at Westmead
RECRUITING

Westmead, New South Wales, 2145, Australia
Tokyo Medical University Hospital
RECRUITING

Shinjuku-ku, Tokyo, 160-0023, Japan
Twoja Przychodnia SCM
RECRUITING

Szczecin, West Pomeranian Voivodeship, 71-434, Poland
UZ Leuven
RECRUITING

Leuven, Vlaams-Brabant, 3000, Belgium
University of Arizona
WITHDRAWN

Tucson, Arizona, 85724, United States
University of California Davis Health
RECRUITING

Sacramento, California, 95817, United States
University of Massachusetts Chan Medical School
RECRUITING

Worcester, Massachusetts, 01655, United States
University of North Carolina Medical Center
WITHDRAWN

Chapel Hill, North Carolina, 27599, United States
Universitätsklinikum Leipzig
RECRUITING

Leipzig, Saxony, 04103, Germany
Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wrocławiu
RECRUITING

Wroclaw, Lower Silesian Voivodeship, 50-369, Poland
WIP Warsaw IBD Point Profesor Kierkuś
RECRUITING

Warsaw, Masovian Voivodeship, 00-728, Poland
Washington University
RECRUITING

St Louis, Missouri, 63110, United States

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