CHRONIC RHINOSINUSITIS WITH NASAL POLYPS

This study tested the drug dupilumab in 63 Chinese adults with chronic sinusitis and nasal polyps (growths in the nose). Participants received either dupilumab injections or a placebo, along with a standard nasal steroid spray, for 24 weeks. The goal was to see if dupilumab could…

This study looked at how safe and effective Xolair is for adults with chronic sinusitis and nasal polyps that don't get better with standard treatments. Researchers tracked side effects and symptom changes in 135 people using Xolair in everyday medical practice. The goal was to s…

This study compared two medications, dupilumab and omalizumab, in 360 adults with severe nasal polyps and asthma. The goal was to see which drug better shrinks polyps and improves sense of smell after 24 weeks. Participants received either drug and were monitored for symptom chan…

This study tested a monthly injection of mepolizumab versus placebo in 95 adults with severe asthma, nasal polyps, and sensitivity to aspirin or similar painkillers. The goal was to see if the drug could improve sinus symptoms and shrink nasal polyps better than placebo. The trea…

This study tested a new injection called TQC2731 in 59 adults with chronic sinusitis and nasal polyps. The goal was to see if it is safe and works well over time. Participants had already completed an earlier study of the same drug. The main focus was on side effects and changes …

This study tested whether taking a low-dose antibiotic (clarithromycin) for three months after sinus surgery could stop nasal polyps from growing back early. 100 patients aged 15-75 took part. Those who received the antibiotic had fewer symptoms and a lower chance of polyps retur…

This study tested the drug dupilumab in 25 adults with chronic sinusitis and nasal polyps that were not well controlled by other treatments. Participants received injections of dupilumab for up to 52 weeks. The main goal was to see if the drug could shrink nasal polyps and improv…

This study tested whether a medication called tezepelumab, given as an injection, could reduce nasal polyps and improve symptoms in people with severe chronic sinusitis. Over 400 participants with severe symptoms who needed surgery received either the drug or a placebo for 52 wee…

This study tested a new drug called lunsekimig in 79 adults with chronic sinusitis and nasal polyps that didn't get better with standard steroid sprays. Participants received either the drug or a placebo as a shot under the skin for 24 weeks. The main goal was to see if the drug …

This study looked at how dupilumab improves smell in people with chronic sinusitis and nasal polyps. Researchers measured changes in inflammation inside the nose using CT scans, endoscopy, and mucus samples. The goal was to confirm that the drug works by directly reducing swellin…