Common antibiotic shows promise in keeping nasal polyps away after surgery
NCT ID NCT07316959
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether taking a low dose of the antibiotic clarithromycin for three months after sinus surgery could prevent nasal polyps from coming back early. 100 adults who had surgery for nasal polyps were split into two groups: one received the antibiotic plus standard care, the other standard care alone. After 12 weeks, only 12% of the antibiotic group had polyp recurrence, compared to 32% in the control group, and they also reported better symptom scores.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- clarithromycin (a macrolide antibiotic)
- What this could lead to
- If confirmed, this could offer a simple, low-cost way to reduce the chance of nasal polyps coming back after surgery.
- What could go wrong
- This was a small, single-center study with only 100 participants. The results need to be repeated in larger, longer trials before becoming standard care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CHRONIC RHINOSINUSITIS WITH NASAL POLYPS are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Muhammad Shouzib Sultan
Lahore, Punjab Province, 54780, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a new drug shrink nasal polyps and restore smell?
- Triple-Action nasal spray could ease chronic sinusitis
- 3D-Printed nose models could boost sinus rinse results
- Sinus surgery may ease sleep problems in nasal polyp patients
- Real-World check: do new biologics really help severe nasal polyps?
- New study digs into how mepolizumab changes nose bacteria and genes in asthma patients