CHRONIC MYELOMONOCYTIC LEUKEMIA
Clinical trials for CHRONIC MYELOMONOCYTIC LEUKEMIA explained in plain language.
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New combo therapy shows promise for leukemia relapse after transplant
Disease control CompletedThis study tested a drug called guadecitabine along with a donor white blood cell infusion in 55 adults whose leukemia or myelodysplastic syndrome came back after a stem cell transplant. The goal was to see if this combination could help the body fight the cancer again. The treat…
Matched conditions: CHRONIC MYELOMONOCYTIC LEUKEMIA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 17, 2026 04:40 UTC
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New Two-Step transplant shows promise for blood cancer patients
Disease control CompletedThis study tested a two-step stem cell transplant for people with blood cancers like leukemia and lymphoma. The approach uses chemotherapy and radiation before donor stem cells are given, followed by drugs to prevent graft-versus-host disease. The goal was to control the cancer a…
Matched conditions: CHRONIC MYELOMONOCYTIC LEUKEMIA
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Experimental combo vaccine and drugs show promise for blood cancers
Disease control CompletedThis early-phase trial tested a combination of a cancer vaccine (CDX-1401), an immune booster (poly ICLC), chemotherapy (decitabine), and an immunotherapy drug (nivolumab) in 8 people with myelodysplastic syndrome (MDS) or low-blast acute myeloid leukemia (AML). The main goal was…
Matched conditions: CHRONIC MYELOMONOCYTIC LEUKEMIA
Phase: PHASE1 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Experimental combo targets tough leukemias
Disease control CompletedThis early-phase study tested a combination of two drugs—veliparib and temozolomide—in 66 adults with acute leukemias that had come back or not responded to standard treatment. The goal was to find the safest dose and see how well the combination worked. Veliparib blocks a repair…
Matched conditions: CHRONIC MYELOMONOCYTIC LEUKEMIA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Experimental cell therapy targets Hard-to-Treat leukemia
Disease control CompletedThis early-phase study tested a new cell therapy called LILRB4 STAR-T cells in one person with monocytic leukemia (a type of blood cancer). The goal was to see if the treatment is safe and can reduce cancer in the bone marrow. Researchers monitored side effects like immune reacti…
Matched conditions: CHRONIC MYELOMONOCYTIC LEUKEMIA
Phase: NA • Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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New drug tested for tough blood cancers
Disease control CompletedThis early-stage study tested a new drug called JNJ-74856665 in 153 people with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS). The main goal was to find safe doses and check for side effects. The drug works by blocking a protein that cancer cells need to grow.
Matched conditions: CHRONIC MYELOMONOCYTIC LEUKEMIA
Phase: PHASE1 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated May 13, 2026 15:58 UTC
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New pill shows promise in early blood cancer trial
Disease control CompletedThis early-stage study tested an oral drug called NTX-301 in 22 adults with certain blood cancers (MDS, AML, or CMML) that had not responded to prior treatment. The main goal was to see if the drug is safe and tolerable, while also checking for any signs that it might help contro…
Matched conditions: CHRONIC MYELOMONOCYTIC LEUKEMIA
Phase: PHASE1 • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated May 11, 2026 20:50 UTC
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New Two-Step transplant shows promise for tough blood cancers
Disease control CompletedThis study tested a two-step stem cell transplant for 62 people with high-risk blood cancers like leukemia and lymphoma. First, patients got low-dose chemotherapy and radiation to prepare the body. Then, they received donor immune cells followed by a stem cell transplant. The goa…
Matched conditions: CHRONIC MYELOMONOCYTIC LEUKEMIA
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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Targeted drug shows promise as Post-Transplant maintenance for rare blood cancers
Disease control CompletedThis study tested the drug enasidenib as a maintenance therapy for people with IDH2-mutant acute myeloid leukemia or chronic myelomonocytic leukemia after a stem cell transplant. The goal was to find the safest dose and see how well patients tolerated it. Twenty-three participant…
Matched conditions: CHRONIC MYELOMONOCYTIC LEUKEMIA
Phase: PHASE1 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 08, 2026 12:00 UTC