Experimental combo shows promise in tough leukemia cases
NCT ID NCT01139970
First seen Nov 16, 2025 · Last updated Jun 12, 2026 · Updated 32 times
Summary
This early-phase study tested a combination of two drugs—veliparib and temozolomide—in 66 adults with acute leukemias that had come back or not responded to standard treatment. The goal was to find the safest dose and see how well the combination worked. Veliparib blocks a repair enzyme in cancer cells, making temozolomide more effective at killing them. The study focused on safety and tumor response, not a cure.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland, 21287, United States
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University of Chicago Comprehensive Cancer Center
Chicago, Illinois, 60637, United States
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University of Maryland/Greenebaum Cancer Center
Baltimore, Maryland, 21201, United States
Conditions
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