New pill takes aim at hard-to-treat blood cancers

NCT ID NCT04609826

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tested a new drug called JNJ-74856665 in 153 people with acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), or chronic myelomonocytic leukemia (CMML). The main goals were to find safe doses and check for side effects when given alone or with other treatments. Participants had cancers that came back or did not respond to standard therapies.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Asan Medical Center

    Seoul, 05505, South Korea

  • CHRU Tours Hopital Bretonneau

    Tours, 37000, France

  • CHU de Nice Hopital de l Archet

    Nice, 06200, France

  • Centre Hospitalier Universitaire (CHU) de Bordeaux Hopital HautLeveque Centre Francois Magendie

    Pessac, 33600, France

  • Clinica Univ. de Navarra

    Pamplona, 31008, Spain

  • Hopital Saint Louis

    Paris, 75010, France

  • Hosp Clinic de Barcelona

    Barcelona, 08036, Spain

  • Hosp Univ Fund Jimenez Diaz

    Madrid, 28040, Spain

  • Hosp Univ Vall D Hebron

    Barcelona, 08035, Spain

  • Hosp. Univ. Marques de Valdecilla

    Santander, 39008, Spain

  • Inst. Cat. Doncologia-H Duran I Reynals

    Barcelona, 08908, Spain

  • Institut Universitaire du Cancer Toulouse Oncopole

    Toulouse, 31059, France

  • Kings College Hospital

    London, SE5 9RF, United Kingdom

  • Leicester Royal Infirmary

    Leicester, LE1 5WW, United Kingdom

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Seoul National University Hospital

    Seoul, 3080, South Korea

  • Severance Hospital Yonsei University Health System

    Seoul, 03722, South Korea

  • The Catholic University of Korea Seoul St Marys Hospital

    Seoul, 06591, South Korea

  • The Christie Nhs Foundation Trust

    Manchester, M20 4BX, United Kingdom

  • University College London Hospitals

    London, NW1 2BU, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.