New combo therapy shows promise for leukemia relapse after transplant

NCT ID NCT02684162

First seen Nov 06, 2025 · Last updated Apr 29, 2026 · Updated 23 times

Summary

This study tested a drug called guadecitabine combined with donor white blood cell infusions in 55 adults whose leukemia or MDS came back after a stem cell transplant. The goal was to see if this combination could safely help patients achieve remission. The approach aims to stop cancer cell growth and boost the immune system's ability to attack remaining cancer cells.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

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