CHRONIC MYELOID LEUKEMIA

This early-stage study is testing a new oral medication called HQP1351 for patients with chronic myeloid leukemia (CML) or a type of acute lymphoblastic leukemia (Ph+ ALL) that has stopped responding to or cannot tolerate standard treatments. The main goals are to find a safe and…

This study is testing whether the drug asciminib can effectively control chronic myeloid leukemia (CML) in adults recently diagnosed with the disease. Researchers will enroll 50 participants to measure how well the drug reduces cancer markers and monitor side effects over time. T…

This study is testing whether a drug called olverembatinib can effectively control newly diagnosed chronic myeloid leukemia (CML) when used alone. It will involve 50 adults with early-stage CML to measure how well the drug reduces cancer markers and manages the disease over time.…

This study is testing whether some patients with chronic myeloid leukemia (CML) who have been in a stable, deep remission for years can safely stop their daily medication. Researchers want to see if these patients can remain cancer-free without treatment, which would spare them f…

This study aims to improve outcomes for patients with high-risk blood cancers who receive a stem cell transplant from a partially matched donor. Researchers are testing a modified combination of two drugs (bendamustine and cyclophosphamide) given after the transplant. The goal is…

This early study is testing if a drug called Darzalex Faspro can safely lower harmful antibodies in patients with blood cancers. Lowering these antibodies may allow patients who are currently ineligible to receive a potentially life-saving stem cell transplant from a donor. The s…

This is the first study in people testing a new drug called MGD024 for several types of blood cancers that have come back or stopped responding to standard treatments. The main goal is to find a safe dose and understand how the drug works in the body. Researchers will also look f…

This early-stage study is testing a new combination of two drugs, selumetinib and azacitidine, for adults with higher-risk chronic myeloid blood cancers like myelodysplastic syndromes (MDS) and myelofibrosis. The main goal is to find the safest and most effective dose by carefull…

This early-stage study is testing a new cell therapy for adults with certain blood cancers who have received a bone marrow transplant from a partially matched family donor. Researchers take a special type of the patient's own immune cells, grow and activate them in a lab, and the…

This early-stage trial is testing a new drug called ELVN-001 for chronic myeloid leukemia (CML). It aims to find the safest dose and see if the drug can reduce leukemia cells in patients whose current treatments have stopped working or caused severe side effects. The study includ…

This study is testing a new daily pill called TERN-701 for adults with chronic myeloid leukemia (CML) who have already tried other treatments. The main goals are to find a safe dose and see if the drug can effectively control the leukemia. The trial will enroll about 180 particip…

This is the first study in people testing a new drug called CBX-250 for several types of advanced blood cancers that have come back or stopped responding to standard treatments. The main goal is to find a safe dose and see how well the body handles the drug, which is given as an …

This early-stage trial is testing a new cell therapy for children and adults whose leukemia has come back or persists after a donor stem cell transplant. Doctors take immune cells (T cells) from the original donor, genetically modify them to better recognize and attack the patien…

This study aims to collect blood and tissue samples to help develop a single blood test that can detect many different cancers early. Researchers will enroll 2,000 people, including those with cancer and those without, to create a reference set for testing. The goal is to validat…

This study aims to understand if a patient's personality is linked to how consistently they take their oral medication for chronic myeloid leukemia (CML). Researchers will recruit 75 people with CML who are on specific cancer drugs. Participants will answer questionnaires about t…