CHRONIC MYELOID LEUKEMIA
Clinical trials for CHRONIC MYELOID LEUKEMIA explained in plain language.
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Leukemia treatment breakthrough tested: can adding interferon help patients stop medication?
Disease control CompletedThis study tested whether adding interferon to the standard drug nilotinib helps newly diagnosed chronic myeloid leukemia patients achieve a deeper reduction in leukemia cells. 200 patients were randomly assigned to receive either nilotinib alone or nilotinib plus interferon for …
Matched conditions: CHRONIC MYELOID LEUKEMIA
Phase: PHASE3 • Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated Apr 02, 2026 00:26 UTC
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Breakthrough trial tests if leukemia patients can ditch daily pills
Disease control CompletedThis study tested whether patients with a specific type of leukemia (CML) who had achieved a very deep remission could safely stop their daily medication, nilotinib. It enrolled 163 adults who had been successfully treated for at least 3 years. The main goal was to see how many p…
Matched conditions: CHRONIC MYELOID LEUKEMIA
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Donor immune cells bolster transplant against blood cancer relapse
Disease control CompletedThis study tested whether adding 'off-the-shelf' natural killer (NK) immune cells from a donor could make stem cell transplants more effective for adults with high-risk forms of leukemia. The goal was to see if this combination was safe and could help prevent the cancer from comi…
Matched conditions: CHRONIC MYELOID LEUKEMIA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 25, 2026 14:07 UTC
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Breakthrough trial aims to free CML patients from lifelong medication
Disease control CompletedThis study tested a two-step approach to help people with chronic myeloid leukemia (CML) live without daily medication. First, it tried reducing the dose of their standard drug (nilotinib). If that didn't work, it tested adding a new drug (asciminib) to try again. The goal was to…
Matched conditions: CHRONIC MYELOID LEUKEMIA
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Mar 18, 2026 14:40 UTC
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Scientists track radioactive drug through healthy volunteers
Knowledge-focused CompletedThis study aimed to understand how the body absorbs, breaks down, and eliminates a new drug candidate (TGRX-678) for chronic myeloid leukemia. Six healthy Chinese male volunteers received a single, traceable dose of the drug. Researchers measured where the drug went and how it le…
Matched conditions: CHRONIC MYELOID LEUKEMIA
Phase: PHASE1 • Sponsor: Shenzhen TargetRx Co., Ltd. • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:30 UTC