CHRONIC MYELOID LEUKEMIA

This study is looking at whether patients with chronic myeloid leukemia (CML) who are already responding well to their medication can safely take a lower dose. Researchers will observe about 100 patients who switch to taking half their usual amount every other day. The goal is to…

This study is testing whether combining two existing cancer drugs, azacitidine and venetoclax, can effectively treat adults with higher-risk chronic myelomonocytic leukemia (CMML), a serious blood and bone marrow disorder. The main goals are to see if the combination is safe and …

This study is testing if using a lower dose of a standard drug (cyclophosphamide) given after a stem cell transplant can reduce serious infections in the first 100 days. The trial aims to see if this lower dose is just as good at preventing graft-versus-host disease, a common and…

This study is for adults with chronic myeloid leukemia (CML) who had to restart their medication after a previous attempt to stop it. It tests if switching to a drug called nilotinib for at least two years can help them successfully stop treatment a second or third time. The main…

This study is testing a modified bone marrow transplant procedure for adults and children with serious blood cancers and disorders. The goal is to treat the underlying disease while reducing the risk of a dangerous complication called graft-versus-host disease. Researchers use a …

This study is testing a specific type of stem cell transplant for patients with various blood cancers. It uses stem cells from a partially matched family donor instead of bone marrow. The main goals are to see how well patients survive and recover, and to learn how the immune sys…

This study observes how well adults with chronic myeloid leukemia stay on Scemblix treatment after trying at least two other therapies. It follows 201 patients in France for 15 months to see if they remain on the medication and how their disease responds. The goal is to understan…

This early-stage study is testing whether immune cells from healthy donors, given along with two other drugs, are safe for people with advanced colorectal, stomach, or hard-to-treat blood cancers. The goal is to see if this combination helps the donor immune cells last longer in …

This study aims to understand how muscle strength and body composition affect recovery and long-term health in people with blood cancers who receive a stem cell transplant. Researchers will observe 144 patients to see if their muscle health at the time of transplant can predict c…