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New drug cocktail shows promise for rare leukemia

NCT ID NCT05768711

Ongoing Disease control Sponsor: Groupe Francophone des Myelodysplasies Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a combination of two drugs, azacitidine and venetoclax, in people with a high-risk form of chronic myelomonocytic leukemia (CMML). The goal is to see if the combo can shrink or control the cancer better than current treatments. About 44 adults will take part, and the study will also check for side effects.

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Conditions

The condition(s) this trial relates to.

chronic myelogenous leukemia, BCR-ABL1 positive chronic myelomonocytic leukemia Leukemia, Myelogenous, Chronic, BCR-ABL Positive

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC MYELOID LEUKEMIA

Contacts and locations

Locations

  • CHRU de Limoges

    Limoges, 87046, France

  • CHU Hôtel Dieu

    Nantes, 44093, France

  • CHU d'Amiens

    Amiens, 80054, France

  • CHU d'Angers

    Angers, 49033, France

  • CHU de Bordeaux - Hôpital Haut-Lévêque

    Pessac, 33604, France

  • CHU de Grenoble

    Grenoble, 38043, France

  • CHU de Montpellier - Hôpital Saint Eloi

    Montpellier, 34295, France

  • CHU de Poitiers

    Poitiers, 86021, France

  • CHU de Tours - Hôpital Bretonneau

    Tours, 37000, France

  • Centre Henri Becquerel

    Rouen, 76038, France

  • Centre Hospitalier Annecy Genevois - Site d'Annecy

    Pringy, 74374, France

  • Centre Hospitalier de Mont de Marsan

    Mont-de-Marsan, 40000, France

  • Centre hospitalier Lyon sud

    Pierre-Bénite, 69495, France

  • Hôpital Archet 1

    Nice, 06200, France

  • Hôpital Avicenne

    Bobigny, 93009, France

  • Hôpital Claude Huriez

    Lille, 59037, France

  • Hôpital Cochin

    Paris, 75014, France

  • Hôpital NOVO

    Pontoise, 95300, France

  • Hôpital Pontchaillou

    Rennes, 35033, France

  • Hôpital Saint Louis

    Paris, 75010, France

  • Hôpital privé Sévigné

    Cesson-Sévigné, 35510, France

  • Hôpital privé du Confluent SAS

    Nantes, 44277, France

  • IUCT oncopole

    Toulouse, 31059, France

  • Institut Gustave Roussy

    Villejuif, 94800, France

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