CHRONIC MIGRAINE

This study follows 100 children under 18 who are already using a ketogenic diet for conditions like drug-resistant epilepsy, autism, chronic migraine, or brain tumors. Researchers want to see if the diet supports healthy growth, improves symptoms, and boosts quality of life over …

This study tests if the drug atogepant can safely prevent chronic migraines in teenagers aged 12 to 17. About 420 teens will take either atogepant or a placebo daily for 12 weeks. The goal is to see if the drug reduces the number of migraine days and is safe for this age group.

This study tests whether adding a daily pill (amitriptyline) to cognitive behavioral therapy (CBT) delivered via video is better than CBT alone for preventing migraines in children aged 7-17. Researchers will track headache days and disability over time. The goal is to find the m…

This study tests an injection called IPN10200 to prevent migraines in adults with episodic or chronic migraine. The drug works by blocking pain-causing chemicals in the brain. About 641 participants will receive either the drug or a placebo to find the safest and most effective d…

This study tests if Xeomin injections can prevent chronic migraines in adults. About 780 people will receive either Xeomin or a placebo injected into head and neck muscles every 12 weeks. The main goal is to see if Xeomin reduces the number of migraine days per month over 6 month…

This study is checking the safety and effectiveness of atogepant, a drug already approved for migraine prevention, in Korean adults. About 3000 people with chronic or episodic migraines will take the drug as prescribed by their doctor and be followed for up to 12 weeks. The goal …

This study tests whether a type of talk therapy called Acceptance and Commitment Therapy (ACT) can help adults with chronic migraine do more of their daily activities. Forty people will either get ACT plus their usual care, or just usual care. Over a year, they will fill out ques…

This study tests whether adding laser acupuncture to standard care can help people with chronic migraine who don't get enough relief from medications. Sixty adults will receive either real or sham laser acupuncture, and researchers will track changes in monthly migraine days, med…

This study tests a device called PRIMUS that uses mild electrical pulses to nerves in the head and neck. It is for people with chronic or frequent migraine who have not found relief from at least three preventive drugs. The goal is to see if the device safely reduces the number o…

This study tests whether a lifestyle behavior program can help people with chronic migraine have fewer and less severe headaches. Researchers will also look for biological markers linked to improvement. The goal is to see if this approach is practical and liked by participants, w…

This study tests whether a non-invasive brain stimulation technique, applied for 20 minutes daily over 20 days, can reduce the number of painful migraine days in people with chronic migraine. About 60 people with chronic migraine will receive either real or sham (fake) stimulatio…

This study is testing how well the drug rimegepant works for treating migraine attacks in 100 adults with episodic or chronic migraine. Researchers will measure pain relief two hours after taking the drug and track any side effects. The goal is to see if rimegepant is effective a…

This study tests a short talk therapy called Well-Being Therapy (WBT) for people with chronic migraine. The goal is to see if it can reduce migraine-related disability, pain, and distress while boosting overall well-being. About 30 adults with chronic migraine will receive either…

This study tests whether cannabis (CBD) can reduce the number of headache days in people with chronic migraines. About 72 adults will receive either a low or high dose of CBD or a placebo. Researchers will compare headache frequency before and after treatment to see if CBD helps …

This study tests a nurse-led mind-body program to help children with migraines have fewer headache days. It will enroll 260 kids aged 10-17 who have migraines with or without aura. The program combines different amounts of three treatment parts to find the best approach for reduc…

This study looks at how well and how safely the drug rimegepant works to prevent migraines. About 100 adults with episodic or chronic migraines will take rimegepant for up to 12 months. Researchers will track changes in the number of migraine days per month to see if the drug red…

This study uses a smartphone app called SOMA to track daily mood, pain, and activity in 800 people with acute or chronic pain, as well as healthy volunteers, over four months. The goal is to find patterns that predict whether pain becomes long-term, improves, or flares up. A smal…