Can online therapy prevent Kids' migraines? new study tests adding a pill

NCT ID NCT05889624

First seen Mar 09, 2026 · Last updated Apr 29, 2026 · Updated 7 times

Summary

This study tests whether adding a daily pill (amitriptyline) to online cognitive behavioral therapy (CBT) helps prevent migraines in children better than online CBT alone. About 400 kids with frequent migraines will participate. The goal is to see which approach reduces headache days and improves daily life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Children's Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cincinnati Children's Hospital Medical Center

    RECRUITING

    Cincinnati, Ohio, 45229, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Clinical Integrative Research Center of Atlanta, Inc

    RECRUITING

    Atlanta, Georgia, 30328, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Dell Children's Hospital-UT Health

    RECRUITING

    Austin, Texas, 78712, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Dent Neurological Institute

    RECRUITING

    Amherst, New York, 14226, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Louisiana State Univ/Children's Hospital of New Orleans

    RECRUITING

    New Orleans, Louisiana, 70118-5720, United States

    Contact Email: •••••@•••••

    Contact

  • Marshall Health

    RECRUITING

    Huntington, West Virginia, 25701, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Nationwide Childrens

    RECRUITING

    Columbus, Ohio, 43205, United States

    Contact

    Contact Email: •••••@•••••

  • Nemours Children's Health System

    RECRUITING

    Wilmington, Delaware, 19810, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Phoenix Children's Hospital - Barrow Neurological Institute

    RECRUITING

    Phoenix, Arizona, 85016-7710, United States

    Contact Email: •••••@•••••

    Contact

  • University of Alabama at Birmingham Children's of Alabama

    RECRUITING

    Birmingham, Alabama, 35233, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of California San Francisco

    RECRUITING

    San Francisco, California, 94115, United States

    Contact

    Contact Email: •••••@•••••

  • University of Colorado/Children's Hospital Colorado

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact

    Contact Email: •••••@•••••

  • University of Louisville Health/Norton

    RECRUITING

    Louisville, Kentucky, 40292, United States

    Contact

    Contact Email: •••••@•••••

  • University of Tennessee Health Science Center/ LeBonheur Children's Hospital

    RECRUITING

    Memphis, Tennessee, 38103, United States

    Contact

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.