Can talk therapy tame chronic migraine? small trial aims to find out
NCT ID NCT03404336
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tests whether Well-Being Therapy, a short psychotherapy focused on building positive mental health, can reduce disability and distress in 30 adults with chronic migraine. Participants will receive either the therapy or a control condition. The goal is to see if this non-drug approach can improve quality of life and reduce migraine burden.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Well-Being Therapy (a brief psychotherapy)
- What this could lead to
- If it works, this could offer a non-drug option to ease migraine-related disability and improve psychological well-being.
- What could go wrong
- This is a very small pilot study (30 people) with no blinding, so results may not be reliable or apply to everyone. The therapy may not reduce migraine attacks.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CHRONIC MIGRAINE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Centro Cefalee e Farmacologia Clinica
RECRUITINGFlorence, Italy, Italy
-
Fiammetta COSCI
NOT_YET_RECRUITINGFlorence, Florence, 50135, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can neck exercises turn down the volume on chronic migraine?
- Can a No-Fridge migraine shot replace botox?
- Could a common cholesterol drug stop chronic migraine?
- Migraine relief may sharpen the mind: study investigates cognitive benefits of preventive therapies
- New combo therapy for chronic migraine: atogepant plus botox under study
- Thousands to test new migraine meds in largest Real-Life study